COBRE: U KS: CORE C: PROTEIN STRUCTURE LABORATORY

COBRE：UK：Core C：蛋白质结构实验室

• 批准号: 8167401
• 负责人: Scott W. Lovell
• 金额: $ 21.78万
• 依托单位: UNIVERSITY OF KANSAS LAWRENCE
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-01 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8167401
• 关键词: Centers of Research Excellence; Computer Retrieval of Information on Scientific Projects Database; Computer software; Crystallization; Data Collection; Doctor of Philosophy; Equipment; Funding; Grant; Housing; Institution; Kansas; Laboratories; Maintenance; Methods; Mission; Proteins; Research; Research Infrastructure; Research Personnel; Resources; Source; Synchrotrons; Time; United States National Institutes of Health; Universities; X ray diffraction analysis; X-Ray Crystallography; X-Ray Diffraction; experience; interest; protein structure; research study; structural biology; three dimensional structure

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. COBRE Core C is also known as the Protein Structure Laboratory (PSL). It is housed in the Structural Biology Center on the West Campus of The University of Kansas. The mission of the Protein Structure Laboratory (PSL) is to assist researchers in obtaining three-dimensional structures of their protein(s) of interest by X-ray crystallography. This is accomplished by maintaining the infrastructure and providing the expertise necessary to conduct crystallographic experiments. To facilitate this, modern crystallization methods, in-house or synchrotron X-ray diffraction data collection, and the most recent crystallographic software are utilized. The staff consists of one experienced full time Ph.D. crystallographer who serves as the Director of the Laboratory, a Core Advisor, and a Research Assistant to conduct equipment maintenance.

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 Cobre Core C也被称为蛋白质结构实验室(PSL)。它位于堪萨斯大学西校区的结构生物学中心。蛋白质结构实验室的任务是帮助研究人员通过X射线结晶学获得他们感兴趣的蛋白质(S)的三维结构。这是通过维护基础设施和提供进行结晶学实验所需的专业知识来实现的。为了促进这一点，使用了现代结晶方法、内部或同步加速器X射线衍射数据收集，以及最新的结晶学软件。工作人员包括一名经验丰富的全职博士结晶师，担任实验室主任，一名核心顾问和一名研究助理，负责设备维护。