PROTOCOL SPECIFIC RESEARCH SUPPORT

丹·L·邓肯癌症中心大力支持研究者发起的早期阶段的发展 临床试验15项最初没有外部支持的由制药商发起的临床试验已经完成， 在过去三年中实施了这些项目，另有10个项目正处于最后开发阶段。的 方案特定研究支持（PSRS）计划为监管和研究提供资金 协调员支持DLDCC发起的此类新型临床试验的协调和实施 investigators. PSRS资源专门用于高优先级的由发射机启动的第1阶段， 在PRMS执行委员会进行科学审查时被判定为具有高度价值的可行性试验 支持的标准包括创新和相关科学研究的存在， 与荒漠化、土地退化和气候变化中心基础或转化科学家合作，或利用荒漠化、土地退化和气候变化中心共享资源。的 高级临床癌症中心领导层已将支持年轻研究人员确定为优先事项， 重点是增加癌症中心临床研究人员的多样性。因此，4项研究中有3项 目前支持的研究由年轻的研究人员领导，其中4名研究人员是少数民族，所有研究都 相关研究。用于评估方案特定支持计划的工具包括 随后收到经同行审查的资金，完成并发表研究报告。PSRS 该计划由执行委员会和外部咨询委员会评估。下一个3的目标 年是支持发起人发起的研究，从发展中的计划或领域， 在荒漠化、土地退化和气候变化协调委员会范围内高度优先发展。

The Dan L Duncan Cancer Center strongly supports the development of investigator-initiated early phase clinical trials. Fifteen investigator-initiated clinical trials that did not initially have external support have been implemented during the last 3 years and an additional 10 are in the final stages of development. The Protocol-Specific Research Support (PSRS) program provides funding for regulatory and research coordinator support for the coordination and implementation of such novel clinical trials initiated by DLDCC investigators. PSRS resources are specifically targeted to high-priority investigator-initiated phase 1 and feasibility trials judged to be of high merit at the time of scientific review by the PRMS executive committee Criteria for support include innovation and the presence of correlative science studies performed in collaboration with DLDCC basic or translational scientists or that utilized DLDCC shared resources. The senior clinical cancer center leadership has identified support of young investigators as a priority and is also focusing on increasing the diversity of cancer center clinical investigators. Consequently, 3 of the 4 studies supported at present are led by young investigators, 4 of the investigators are minorities and all studies have associated correlative studies. Metrics for evaluation of the protocol specific support program include subsequent receipt of peer-reviewed funding and completion and publication of the study. The PSRS program is evaluated by both the Executive Committee and the External Advisory Board. A goal in the next 3 years is to support investigator-initiated studies that emanate from the developing programs or areas that are of high priority to develop within the DLDCC.