PROTOCOL SPECIFIC RESEARCH SUPPORT

特定于协议的研究支持

• 批准号: 8181022
• 负责人: SUSAN M. BLANEY
• 金额: $ 3.68万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-17 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8181022
• 关键词: African American; American; Antigen Receptors; Antigens; Area; Award; B lymphoid malignancy; B-Lymphocytes; Basic Science; Bioinformatics; Blood; Bone Marrow Transplantation; Breast; Cancer Center; Clinical; Clinical Cancer Center; Clinical Investigator; Clinical Research; Clinical Trials; Collaborations; Commit; Communities; Correlative Study; Detection; Development; Devices; Diagnosis; Evaluation; Faculty; Fellowship; Foundations; Funding; Gene Transfer; Generations; Goals; Hispanics; Hospitals; K-Series Research Career Programs; Laboratory Study; Lead; Leadership; Malignant - descriptor; Malignant Neoplasms; Medicine; Mentors; Methodist Church; Metric; Minority; NCI Center for Cancer Research; Pacific Island Americans; Pediatric Oncology; Peer Review; Phase; Prevention; Principal Investigator; Protocols documentation; Publications; Recommendation; Research; Research Institute; Research Personnel; Research Support; Resource Allocation; Resource Sharing; Resources; Review Committee; SECTM1 gene; Science; Scientist; Secure; Societies; Staging; T-Lymphocyte; Time; Transplantation; Work; base; cancer therapy; career development; college; design; innovation; member; novel; patient population; pre-clinical; preference; programs

The Dan L Duncan Cancer Center strongly supports the development of investigator-initiated early phase clinical trials. Fifteen investigator-initiated clinical trials that did not initially have external support have been implemented during the last 3 years and an additional 10 are in the final stages of development. The Protocol-Specific Research Support (PSRS) program provides funding for regulatory and research coordinator support for the coordination and implementation of such novel clinical trials initiated by DLDCC investigators. PSRS resources are specifically targeted to high-priority investigator-initiated phase 1 and feasibility trials judged to be of high merit at the time of scientific review by the PRMS executive committee Criteria for support include innovation and the presence of correlative science studies performed in collaboration with DLDCC basic or translational scientists or that utilized DLDCC shared resources. The senior clinical cancer center leadership has identified support of young investigators as a priority and is also focusing on increasing the diversity of cancer center clinical investigators. Consequently, 3 of the 4 studies supported at present are led by young investigators, 4 of the investigators are minorities and all studies have associated correlative studies. Metrics for evaluation of the protocol specific support program include subsequent receipt of peer-reviewed funding and completion and publication of the study. The PSRS program is evaluated by both the Executive Committee and the External Advisory Board. A goal in the next 3 years is to support investigator-initiated studies that emanate from the developing programs or areas that are of high priority to develop within the DLDCC.

Dan L Duncan 癌症中心大力支持研究者发起的早期阶段的开发 临床试验。十五项由研究者发起、最初没有外部支持的临床试验已被批准 过去 3 年实施，另外 10 个项目正处于开发的最后阶段。这 特定协议研究支持 (PSRS) 计划为监管和研究提供资金 协调员支持 DLDCC 发起的此类新型临床试验的协调和实施 调查人员。 PSRS 资源专门针对研究者发起的高优先级第一阶段和 PRMS执行委员会在进行科学审查时认为可行性试验具有很高的价值 支持的标准包括创新和相关科学研究的存在 与 DLDCC 基础科学家或转化科学家合作，或利用 DLDCC 共享资源。这 临床癌症中心高级领导层已将年轻研究人员的支持确定为优先事项，并且 专注于增加癌症中心临床研究人员的多样性。因此，4 项研究中有 3 项 目前支持的研究由年轻研究者领导，其中 4 名研究者是少数族裔，所有研究均已 相关的相关研究。协议特定支持计划的评估指标包括 随后收到同行评审的资金以及研究的完成和出版。公共服务RS 计划由执行委员会和外部顾问委员会评估。未来3个进球 年的目的是支持研究者发起的研究，这些研究源于正在开发的计划或领域 DLDCC 内优先发展的项目。