PROTOCOL SPECIFIC RESEARCH SUPPORT

特定于协议的研究支持

• 批准号: 8181022
• 负责人: SUSAN M. BLANEY
• 金额: $ 3.68万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-17 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8181022
• 关键词: African American; American; Antigen Receptors; Antigens; Area; Award; B lymphoid malignancy; B-Lymphocytes; Basic Science; Bioinformatics; Blood; Bone Marrow Transplantation; Breast; Cancer Center; Clinical; Clinical Cancer Center; Clinical Investigator; Clinical Research; Clinical Trials; Collaborations; Commit; Communities; Correlative Study; Detection; Development; Devices; Diagnosis; Evaluation; Faculty; Fellowship; Foundations; Funding; Gene Transfer; Generations; Goals; Hispanics; Hospitals; K-Series Research Career Programs; Laboratory Study; Lead; Leadership; Malignant - descriptor; Malignant Neoplasms; Medicine; Mentors; Methodist Church; Metric; Minority; NCI Center for Cancer Research; Pacific Island Americans; Pediatric Oncology; Peer Review; Phase; Prevention; Principal Investigator; Protocols documentation; Publications; Recommendation; Research; Research Institute; Research Personnel; Research Support; Resource Allocation; Resource Sharing; Resources; Review Committee; SECTM1 gene; Science; Scientist; Secure; Societies; Staging; T-Lymphocyte; Time; Transplantation; Work; base; cancer therapy; career development; college; design; innovation; member; novel; patient population; pre-clinical; preference; programs

The Dan L Duncan Cancer Center strongly supports the development of investigator-initiated early phase clinical trials. Fifteen investigator-initiated clinical trials that did not initially have external support have been implemented during the last 3 years and an additional 10 are in the final stages of development. The Protocol-Specific Research Support (PSRS) program provides funding for regulatory and research coordinator support for the coordination and implementation of such novel clinical trials initiated by DLDCC investigators. PSRS resources are specifically targeted to high-priority investigator-initiated phase 1 and feasibility trials judged to be of high merit at the time of scientific review by the PRMS executive committee Criteria for support include innovation and the presence of correlative science studies performed in collaboration with DLDCC basic or translational scientists or that utilized DLDCC shared resources. The senior clinical cancer center leadership has identified support of young investigators as a priority and is also focusing on increasing the diversity of cancer center clinical investigators. Consequently, 3 of the 4 studies supported at present are led by young investigators, 4 of the investigators are minorities and all studies have associated correlative studies. Metrics for evaluation of the protocol specific support program include subsequent receipt of peer-reviewed funding and completion and publication of the study. The PSRS program is evaluated by both the Executive Committee and the External Advisory Board. A goal in the next 3 years is to support investigator-initiated studies that emanate from the developing programs or areas that are of high priority to develop within the DLDCC.

Dan L Duncan癌症中心强烈支持研究人员发起的早期阶段的发展 临床试验。最初没有外部支持的15个研究者发射的临床试验是 在过去的3年中实施，另外10个是在开发的最后阶段。这 特定于协议的研究支持（PSRS）计划为监管和研究提供资金 协调员支持DLDCC发起的这种新型临床试验的协调和实施 调查人员。 PSRS资源专门针对高优先级研究者发起的第1阶段和 PRMS执行委员会的科学审查时，可行性试验被认为具有很高的优点 支持的标准包括创新和存在的相关科学研究的存在 与DLDCC基本或翻译科学家或使用DLDCC共享资源的合作。这 高级临床癌症中心领导领导已确定年轻研究人员的支持是优先事项，也是 专注于增加癌症中心临床研究人员的多样性。因此，这四个研究中有3项 目前由年轻调查员领导的目前支持的4个研究人员是少数群体，所有研究 相关的相关研究。评估协议特定支持计划的指标包括 随后收到同行评审的资金以及该研究的完成和发布。 PSR 程序均由执行委员会和外部顾问委员会评估。接下来的3个目标 多年是为了支持研究者发动的研究，这些研究从发展的计划或领域发出 在DLDCC中发展的高度优先级。