4D FLOW EVALUATION OF ABNORMAL SYSTOLIC FLOW PATTERNS WITH BICUSPID AORTIC VALVE

该子项目是利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得主要资金， 因此可以在其他CRISP条目中表示。列出的机构是 中心，不一定是研究者的机构。 血流动力学改变在二叶式主动脉瓣（BAV）患者胸升主动脉扩张中的作用存在争议。我们采用4D Flow MR成像来评价收缩期血流模式，目的是发现异常，这可能有助于我们了解BAV患者发生动脉瘤和夹层的风险增加的原因。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The role altered hemodynamics play in dilation of the ascending thoracic aorta in bicuspid aortic valve (BAV) patients is controversial. We have employed 4D Flow MR imaging to evaluate systolic blood flow patterns with the goal of uncovering abnormalities that may inform our understanding of why BAV patients are at increased risk for aneurysm and dissection.