METABOLOMICS OF STEAROYL-COA KO MICE

该子项目是利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得主要资金， 因此可以在其他CRISP条目中表示。列出的机构是 中心，不一定是研究者的机构。 与对照小鼠相比，硬脂酰辅酶A去饱和酶敲除小鼠显示出一些有趣的代谢表型。为了更好地了解这些表型，我们将分析它们肝脏中代谢物水平的差异。为此，我们期望更好地了解这些KO小鼠的代谢调节

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Stearoyl-CoA desaturase knock-out mice have shown some interesting metabolic phenotypes when compared to control mice. In order to better understand these phenotypes we will analyze the differences of levels of metabolites in their livers. To this end we expect to gain a better understanding of the metabolic regulations in these KO mice