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MODULATION OF ABETA PEPTIDE ACCUMULATION AND NEURON DAMAGE IN VIVO WITH ADULT BON

MODULATION OF ABETA PEPTIDE ACCUMULATION AND NEURON DAMAGE IN VIVO WITH ADULT BON
使用 ADULT BON 调节体内 ABETA 肽积累和神经元损伤
批准号：
8014542
负责人：
CHRISTOPHER DIRK KEENE
金额：
$19.5万
依托单位：
UNIVERSITY OF WASHINGTON
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/8014542
关键词：
AbbreviationsAddressAdultAllogenicAlzheimer&aposs DiseaseAmyloidAmyloid beta-ProteinAreaAutologousBone MarrowBone Marrow TransplantationBrainCell TransplantsCellsCerebrumChronic DiseaseClinicalComplementDataDepositionDiseaseEngraftmentExclusionFoundationsFundingFutureGeneticGenetically Engineered MouseHematopoietic stem cellsHippocampus (Brain)HumanImmune responseImmunologicsIndividualKnowledgeLifeLupusMalignant NeoplasmsMarrowMeasuresMediatingMedicalMethodsMicrogliaModalityMultiple SclerosisMusNeurodegenerative DisordersNeuronsNeurotoxinsNon-MalignantPathway interactionsPeptide MetabolismPeptidesPeripheralPhagocytosisProceduresProstaglandin E ReceptorProstaglandinsProstaglandins EProtocols documentationRadiationReactionResourcesRheumatoid ArthritisSafetySenile PlaquesTechnologyTestingTherapeuticToxic effectTransgenic MiceTransplantationTreatment EfficacyUnited States National Institutes of HealthWorkamyloid peptidebasecell typeclinical applicationclinically relevantcytokineeffective therapygene therapygenetic manipulationimmunoregulationin vivomouse modelneuroprotectionneurotoxicneurotoxicitynovelnovel therapeutic interventionnovel therapeuticsolder patientparacrinepeptide Bpreconditioningreceptorresearch studyresponsevirtual

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