NEURONAL AXONS (AXONS FROM DRG NEURONS)
NEURONAL AXONS (AXONS FROM DRG NEURONS)
批准号:
8168600
负责人:
William C Mobley
金额:
$0.65万
依托单位国家:
美国
项目类别:
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-01-15 至 2010-12-31
中文摘要
该子项目是利用
由NIH/NCRR资助的中心赠款提供的资源。子项目和
研究者(PI)可能从另一个NIH来源获得主要资金,
因此可以在其他CRISP条目中表示。列出的机构是
中心,不一定是研究者的机构。
轴突是神经元之间货物运输和通信的“高速公路”。了解神经退行性神经元轴突与健康轴突的轴突亚结构变化是很重要的。这些轴突3D亚结构变化可以使用冷冻ET采集的数据进行注释。
英文摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
Axons are the "highways" of cargo transport and communication between neurons. It is important to understand the axonal sub-structural changes in neurodegenerating neurons' axons vs. healthy axons. These axonal 3D sub-structural changes can be annotated using cryo-ET acquired data.
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会议论文
Antisense Oligonucleotides targeting APP to prevent neurodegeneration in models of Down Syndrome and Alzheimer's disease
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批准号:10554249
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项目类别:
-
资助金额:$64.25万
-
财政年份:2019
-
负责人:William C Mobley
-
依托单位:
Antisense Oligonucleotides targeting APP to prevent neurodegeneration in models of Down Syndrome and Alzheimer's disease
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批准号:10543710
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项目类别:
-
资助金额:$27.03万
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财政年份:2019
-
负责人:William C Mobley
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依托单位:
Antisense Oligonucleotides targeting APP to prevent neurodegeneration in models of Down Syndrome and Alzheimer's disease
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批准号:9905472
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项目类别:
-
资助金额:$56.76万
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财政年份:2019
-
负责人:William C Mobley
-
依托单位:
Antisense Oligonucleotides targeting APP to prevent neurodegeneration in models of Down Syndrome and Alzheimer's disease
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批准号:10334410
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项目类别:
-
资助金额:$70.2万
-
财政年份:2019
-
负责人:William C Mobley
-
依托单位:
Antisense Oligonucleotides targeting APP to prevent neurodegeneration in models of Down Syndrome and Alzheimer's disease
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批准号:10092057
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项目类别:
-
资助金额:$73.21万
-
财政年份:2019
-
负责人:William C Mobley
-
依托单位:
Treating with Gamma-Secretase Modulators to Prevent Neurodegeneration in Mouse Models of Down Syndrome and Alzheimer Disease
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批准号:10338158
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项目类别:
-
资助金额:$51.63万
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财政年份:2018
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负责人:William C Mobley
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依托单位:
Alzheimer's Disease Cooperative Study
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批准号:9021933
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项目类别:
-
资助金额:$9.96万
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财政年份:2015
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负责人:William C Mobley
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依托单位:
NEURONAL AXONS (AXONS FROM DRG NEURONS)
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批准号:8361107
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项目类别:
-
资助金额:$0.74万
-
财政年份:2011
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负责人:William C Mobley
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依托单位:
Genetic Basis of Failed Cognition in Young and Aged Mouse Models of Trisomy 21
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批准号:8145581
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项目类别:
-
资助金额:$64.55万
-
财政年份:2010
-
负责人:William C Mobley
-
依托单位:
Genetic Basis of Failed Cognition in Young and Aged Mouse Models of Trisomy 21
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批准号:8725237
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项目类别:
-
资助金额:$63.91万
-
财政年份:2010
-
负责人:William C Mobley
-
依托单位:
Genetic Basis of Failed Cognition in Young and Aged Mouse Models of Trisomy 21
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批准号:8520060
-
项目类别:
-
资助金额:$62.3万
-
财政年份:2010
-
负责人:William C Mobley
-
依托单位:
Genetic Basis of Failed Cognition in Young and Aged Mouse Models of Trisomy 21
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批准号:8323834
-
项目类别:
-
资助金额:$64.55万
-
财政年份:2010
-
负责人:William C Mobley
-
依托单位:
Genetic Basis of Failed Cognition in Young and Aged Mouse Models of Trisomy 21
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批准号:7890887
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项目类别:
-
资助金额:$67.15万
-
财政年份:2010
-
负责人:William C Mobley
-
依托单位:
2009 Neurotrophic Factors Gordon Research Conference
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批准号:7672016
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项目类别:
-
资助金额:$2.7万
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财政年份:2009
-
负责人:William C Mobley
-
依托单位:
Disrupted Transport of NGF-TrKA Signaling in Mouse Models of Down Syndrome
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批准号:7418274
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项目类别:
-
资助金额:$36.95万
-
财政年份:2007
-
负责人:William C Mobley
-
依托单位:
Disrupted Transport of NGF-TrKA Signaling in Mouse Models of Down Syndrome
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批准号:7212688
-
项目类别:
-
资助金额:$30.49万
-
财政年份:2007
-
负责人:William C Mobley
-
依托单位:
Disrupted Transport of NGF-TrKA Signaling in Mouse Models of Down Syndrome
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批准号:8034074
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项目类别:
-
资助金额:$31.66万
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财政年份:2007
-
负责人:William C Mobley
-
依托单位:
Disrupted Transport of NGF-TrKA Signaling in Mouse Models of Down Syndrome
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批准号:7825358
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项目类别:
-
资助金额:$51.87万
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财政年份:2007
-
负责人:William C Mobley
-
依托单位:
Disrupted Transport of NGF-TrKA Signaling in Mouse Models of Down Syndrome
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批准号:7617094
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项目类别:
-
资助金额:$10.2万
-
财政年份:2007
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负责人:William C Mobley
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依托单位:
Training in Translational Develomental Neuroscience
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批准号:6935916
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项目类别:
-
资助金额:$28.46万
-
财政年份:2004
-
负责人:William C Mobley
-
依托单位:
海外基金