AUTOMATED SAMPLE MOUNTING SYSTEM

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 最苛刻的结晶学问题涉及广泛的筛选研究，以确定最佳晶体生长方案，或从一批类似晶体中发现最好的晶体以进行数据收集。进入终端站机柜安装水晶、启动安全联锁、关闭机柜门并将探测器移动到适当位置所需的时间是获取一个“平均”数据集所需时间的一半以上。远程样品安装自动化消除了这些后勤浪费，并极大地提高了波动光束线上数据采集的效率。 我们重新设计和重建了ALS气动机器人，最初在8-BM投入使用，以兼容和使用24-ID-C。该设备已完全运行，所有用户均可使用。该系统在单位时间的数据集数量方面有效地将光束线的效率提高了一倍。样品安装机器人将建造和安装在2-ID-E和24-BM-B上。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Most demanding crystallographic problems involve extensive screening studies to define optimal crystal growth protocols or to discover the best crystals from a batch of similar crystals for data collection. The time required to enter the endstation hutch mount a crystal, actuate the safety interlocks, close the hutch door and move the detector into position is more than half the time required to acquire an "average" data set. Remote sample mounting automation eliminates these logistical wastes and greatly increases the efficiency of data collection at undulator beam lines. We have redesigned and rebuilt the ALS pneumatic robot originally commissioned at 8-BM for compatibility and use on 24-ID-C. This device is fully operational and available to all users. The system effectively doubles the efficiency of the beam line in terms of number of data sets per unit time. Sample mounting robots will be built and installed on 2-ID-E and 24-BM-B.