CYTOSL-VESICLE-VACUOLE PROTEIN DEGRADATION PATHWAY

细胞质-囊泡-液泡蛋白降解途径

• 批准号: 8171461
• 负责人: HUI-LING CHIANG
• 金额: $ 0.14万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-01 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8171461
• 关键词: Aging; Autophagocytosis; Computer Retrieval of Information on Scientific Projects Database; Degradation Pathway; Funding; Grant; Institution; Lead; Malignant Neoplasms; Organelles; Process; Proteins; Research; Research Personnel; Resources; Source; Therapeutic; United States National Institutes of Health; Vacuole; diabetic; protein degradation; vesicle/vacuole

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Autophagy is a process whereby proteins and organelles are degraded in the vacuole. Altered autophagy is associated with cancer, aging and diabetics. Understanding how autophagy is regulated may lead to therapeutic strategies to eliminate abnormal proteins that accumulate in various pathological conditions.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 自噬是蛋白质和细胞器在液泡中降解的过程。改变的自噬与癌症、衰老和糖尿病有关。了解自噬是如何调节的可能会导致治疗策略，以消除在各种病理条件下积累的异常蛋白质。