MOLECULAR FUNCTION OF XCT, A CONSERVED CLOCK-ASSOCIATED GENE

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 我们已经克隆了一个新的基因，XCT，它对时钟功能和光信号具有重要作用 在植物中。XCT在真核生物中高度保守，对 后生动物，但在任何生物体中都没有已知的分子功能。我们将使用基因和 用生物化学技术确定裂解酵母和植物的分子作用模式 XCT的。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We have cloned a novel gene, XCT, which is important for clock function and light signaling in plants. XCT is highly conserved across eukaryotes, is essential for development in metazoa, but has no known molecular function in any organism. We will use genetic and biochemical techniques in fission yeast and plants to determine the molecular mode of action of XCT.