MOLECULAR FUNCTION OF XCT, A CONSERVED CLOCK-ASSOCIATED GENE

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 我们克隆了一个新的基因，XCT，它在植物的时钟功能和光信号转导中起重要作用。XCT在真核生物中高度保守，对于后生动物的发育是必不可少的，但在任何生物体中都没有已知的分子功能。我们将在分裂酵母和植物中使用遗传和生化技术来确定XCT的分子作用模式。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We have cloned a novel gene, XCT, which is important for clock function and light signaling in plants. XCT is highly conserved across eukaryotes, is essential for development in metazoa, but has no known molecular function in any organism. We will use genetic and biochemical techniques in fission yeast and plants to determine the molecular mode of action of XCT.