BIOCHEMICAL ANALYSIS OF CENTROSOMAL PROTEIN COMPLEXES

中心体蛋白复合物的生化分析

• 批准号: 8171470
• 负责人: ALEXANDER DAMMERMANN
• 金额: $ 0.08万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-01 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8171470
• 关键词: Animals; Biochemical; Biochemistry; Caenorhabditis elegans; Cells; Centrosome; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Institution; Laboratories; Microtubule-Organizing Center; Modeling; Organism; Proteins; Research; Research Personnel; Resources; Source; United States National Institutes of Health; Work; interest; protein complex

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Centrosomes are the primary microtubule organizing centers in animal cells. Our laboratory is interested in determining how centrosomes assemble and function, using C. elegans as a model. Previous work in a number of laboratories has identified ~15 proteins required for centrosome function in this organism. We are currently using biochemistry to further characterize these proteins and identify additional proteins by virtue of their interaction with known centrosomal proteins.

这个子项目是众多研究子项目之一