DYNAMICS OF PROTEASOME COMPLEXES & THEIR INTERACTIONS WITH CSN COMPLEXES

蛋白酶体复合物的动力学

• 批准号: 8171000
• 负责人: Lan Huang
• 金额: $ 0.18万
• 依托单位: UNIVERSITY OF CALIFORNIA-IRVINE
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-01 至 2011-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8171000
• 关键词: Complex; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Institution; Oxidative Stress; Research; Research Personnel; Resources; Source; Structure; United States National Institutes of Health; in vivo; interest; multicatalytic endopeptidase complex

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We are interested in understanding how the structures of proteasome complexes are regulated upon oxidative stress. In addition, we are trying to determine how proteasome complexes interact with the CSN complex in vivo.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 我们有兴趣了解蛋白酶体复合物的结构是如何调节氧化应激。 此外，我们正试图确定蛋白酶体复合物如何在体内与CSN复合物相互作用。