HIGH-RESOLUTION 3D DIFFUSION TENSOR IMAGING OF MOUSE BRAIN

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 三维扩散张量成像在确定脑组织的组织和整合方面非常有用。由于低信号和大数据量，高分辨率很难实现。在这项研究中，我们试图利用先进的硬件、序列和后处理技术的组合，在小鼠的大脑中实现创纪录的各向同性分辨率。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. 3D diffusion tensor imaging is very useful in defining organization and integration of the brain tissue. High resolution is difficult to achieve, due to low signal and large data size. In this study, we are trying to achieve record-high isotropic resolution in mouse brain utilizing a combination of advance hardware, sequence, and post-processing techniques.