HIGH-RESOLUTION 3D DIFFUSION TENSOR IMAGING OF MOUSE BRAIN

小鼠大脑的高分辨率 3D 扩散张量成像

• 批准号: 8363168
• 负责人: Yi Jiang
• 金额: $ 1.84万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-01 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8363168
• 关键词: Brain; Data; Diffusion Magnetic Resonance Imaging; Funding; Grant; Microscopy; Mus; National Center for Research Resources; Principal Investigator; Process; Research; Research Infrastructure; Resolution; Resources; Signal Transduction; Source; Techniques; United States National Institutes of Health; brain tissue; cost

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. 3D diffusion tensor imaging is very useful in defining organization and integration of the brain tissue. High resolution is difficult to achieve, due to low signal and large data size. In this study, we are trying to achieve record-high isotropic resolution in mouse brain utilizing a combination of advance hardware, sequence, and post-processing techniques.

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 子项目的主要研究者可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 3D扩散张量成像在定义脑组织的组织和整合方面非常有用。由于低信号和大数据大小，高分辨率难以实现。在这项研究中，我们试图实现记录高分辨率的各向同性在小鼠大脑利用先进的硬件，序列和后处理技术的组合。