CHARACTERIZATION OF LIQUID AMORPHOUS CALCIUM CARBONATE PHASES BY IN SITU XAS

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 从饱和碳酸氢钙溶液（即硬水）中形成碳酸钙（白垩）的过程是在中性 pH 值（这是活体动物或海水中矿物质形成的典型情况）下通过一种非常不常见的液体中间体进行的，该液体中间体非常稳定且具有纳米尺寸。该项目的目标是原位表征沉淀过程中发生的机制和中间钙化合物。所采用的悬浮液滴技术可以原位监测碳酸钙的均质结晶，同时避免任何可能通过异质成核影响沉淀过程的异质相边界。 了解经典生物矿物形成的基础知识对于仿生或仿生新材料以及骨植入物和骨/牙齿替代材料的开发至关重要。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The formation of calcium carbonate (chalk) from a saturated calcium bicarbonate solution (i.e. hard water) proceeds at neutral pH (which is typical for the formation of minerals in living animals or sea water) via a very uncommon liquid intermediate, which is remarkable stable and nanosized. The goal of this project is to characterize in situ the mechanism and the intermediate calcium compounds which occur during this precipitation. The employed levitated droplet technique allows an in situ monitoring of the homogenous crystallization of calcium carbonate while avoiding any foreign phase boundaries that may influence the precipitation process by heterogeneous nucleation. Understanding the basics of classical biomineral formation is essential for biomimetic or bio-inspired new materials and for the development of bone implants and bone/teeth substitute materials.