CHARACTERIZATION OF LIQUID AMORPHOUS CALCIUM CARBONATE PHASES BY IN SITU XAS

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， NCRR赠款不直接向子项目或子项目工作人员提供资金。 由饱和碳酸氢钙溶液（即硬水）形成碳酸钙（白垩）在中性pH值（这对于在活动物或海水中形成矿物质是典型的）下通过非常不常见的液体中间体进行，该液体中间体非常稳定且具有纳米尺寸。该项目的目标是原位表征该沉淀过程中发生的机制和中间钙化合物。所采用的悬浮液滴技术允许原位监测碳酸钙的均匀结晶，同时避免可能通过异相成核影响沉淀过程的任何外来相边界。 了解经典生物矿物形成的基础知识对于仿生或生物启发的新材料以及骨植入物和骨/牙齿替代材料的开发至关重要。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The formation of calcium carbonate (chalk) from a saturated calcium bicarbonate solution (i.e. hard water) proceeds at neutral pH (which is typical for the formation of minerals in living animals or sea water) via a very uncommon liquid intermediate, which is remarkable stable and nanosized. The goal of this project is to characterize in situ the mechanism and the intermediate calcium compounds which occur during this precipitation. The employed levitated droplet technique allows an in situ monitoring of the homogenous crystallization of calcium carbonate while avoiding any foreign phase boundaries that may influence the precipitation process by heterogeneous nucleation. Understanding the basics of classical biomineral formation is essential for biomimetic or bio-inspired new materials and for the development of bone implants and bone/teeth substitute materials.