课题基金 / 基金详情

MUCOSAL IMMUNITY AND HETEROLOGOUS PROTECTION INDUCED BY SINGLE-CYCLE SIV

MUCOSAL IMMUNITY AND HETEROLOGOUS PROTECTION INDUCED BY SINGLE-CYCLE SIV
单周期 SIV 诱导的粘膜免疫和异源保护
批准号：
8172869
负责人：
David T Evans
金额：
$20.24万
依托单位：
HARVARD MEDICAL SCHOOL
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
项目状态：
已结题
起止时间：
2010-05-01 至 2011-04-30
来源：
https://reporter.nih.gov/project-details/8172869
关键词：
ComplementComputer Retrieval of Information on Scientific Projects DatabaseCytoprotectionFundingGrantHomingImmunizationInstitutionIntravenousMacaca mulattaMucosal ImmunityPropertyResearchResearch PersonnelResourcesRouteSIVSiteSourceT-LymphocyteUnited States National Institutes of HealthVesicular stomatitis Indiana virusVirussubcutaneous

项目摘要

项目成果

David T Evans的其他基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. To determine if the site of immunization influences the mucosal homing properties of virus-specific T cells, and protection against a mucosal challenge, separate groups of rhesus macaques were immunized by intravenous versus subcutaneous routes of inoculation with VSV G trans-complemented single-cycle SIV, and challenged by intrarectal inoculaton with wild-type SIV.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Evaluation of didehydro-Cortistatin A as a block-and-lock agent for a functional HIV cure in a macaque model
  • 批准号：
    10403162
  • 项目类别：
  • 资助金额：
    $44.11万
  • 财政年份：
    2021
  • 负责人：
    David T Evans
  • 依托单位：
    SCRIPPS FLORIDA
Evaluation of didehydro-Cortistatin A as a block-and-lock agent for a functional HIV cure in a macaque model
  • 批准号：
    10591883
  • 项目类别：
  • 资助金额：
    $45.09万
  • 财政年份：
    2021
  • 负责人：
    David T Evans
  • 依托单位：
    UNIVERSITY OF FLORIDA
Tethering lentiviral restriction to Fc-mediated antibody responses
  • 批准号：
    10425358
  • 项目类别：
  • 资助金额：
    $70.77万
  • 财政年份：
    2020
  • 负责人：
    David T Evans
  • 依托单位：
    UNIVERSITY OF WISCONSIN-MADISON
Tethering lentiviral restriction to Fc-mediated antibody responses
  • 批准号：
    10082732
  • 项目类别：
  • 资助金额：
    $45.44万
  • 财政年份：
    2020
  • 负责人：
    David T Evans
  • 依托单位：
    UNIVERSITY OF WISCONSIN-MADISON