Center for Education and Research on Mental Health Therapeutics

描述（由申请人提供）： 罗格斯-哥伦比亚心理健康治疗教育和研究中心将专注于安全有效地使用行为健康障碍患者的治疗方法。中心的项目和活动将解决关键差距 在证据基础上的精神卫生治疗和服务系统创新的比较有效性。我们将建立在基础设施，合作伙伴关系，数据集开发和研究线的坚实基础上，从我们作为CERT研究中心的第一个五年的工作中，以解决所有五个程序感兴趣的领域。拟议的工作将通过一个咨询委员会，由系统的利益相关者输入指导，该委员会代表能够将中心的发现转化为改进的护理流程和结果的组织。研究和教育活动将得到数据，方法和生物统计核心以及教育，翻译和利益相关者核心的支持，并在以人口为基础的核心内组织1）青年，2）成年人，3）体弱的老年人。具体项目包括：1）管理难治性精神分裂症的替代药理学策略的比较有效性分析，2）基于全州社区精神卫生中心的创新医疗之家模式对安全有效使用精神卫生治疗的影响分析，3）抗痴呆药物在养老院老年人中的比较安全性分析，4）检查结构化诊断访谈对严重精神障碍青年的管理和结局的潜在影响，5）评估精神分裂症患者的过早死亡率及其一般医疗护理的潜在质量。通过这些项目和相关的教育活动，该中心的目标是作为一个值得信赖的国家资源，为心理健康利益相关者的决策提供信息，重点是广泛的人群-接受治疗，特别是在医疗补助和医疗保险中。 我们与各州和联邦政策制定者合作的经验也使我们有资格领导涉及医疗补助机构和复杂、高成本患者的新的跨CERT计划 公共卫生相关性：精神健康状况占总体疾病负担和卫生保健支出的很大一部分，并使其他医学疾病的病程和治疗大大复杂化。 该中心的工作将解决这些关键问题，作为一个国家观察站，在大型的日常护理环境中使用心理健康治疗和结果，与主要利益攸关方建立强有力的伙伴关系。

DESCRIPTION (provided by applicant): The Rutgers-Columbia Center for Education and Research on Mental Health Therapeutics will focus on safe and effective use of therapeutics for persons with behavioral health disorders. Center projects and activities will address critical gaps in the evidence base on the comparative effectiveness of mental health treatments and services system innovations. We will build on the solid foundation of infrastructure, partnerships, dataset development, and lines of research from our first five years of work as a CERTs Research Center to address all five programmatic interest areas. The proposed work will be guided by systematic stakeholder input through an advisory committee representing organizations that are well positioned to translate Center findings into improved care processes and outcomes. Research and educational activities will be supported by a Data, Methods and Biostatistics Core and an Education, Translation and Stakeholder Core and organized within population-based cores for 1) youth, 2) adults, and 3) the frail elderly. Specific projects include: 1) a comparativ effectiveness analysis of alternative pharmacological strategies to manage treatment-resistant schizophrenia, 2) an analysis of the impact of an innovative statewide community mental health center-based medical home model for the safe and effective use of mental health therapeutics, 3) a comparative safety analysis of anti-dementia medications in the nursing home elderly, 4) an examination of the potential impact of structured diagnostic interviewing on the management and outcome of youth with severe psychiatric disorders, and 5) an assessment of premature mortality in schizophrenia patients and their underlying quality of general medical care. Through these projects and related educational activities, the Center aims to serve as a trusted national resource to inform decision's making of mental health stakeholders, with an emphasis on broad populations -under treatment, especially in Medicaid and Medicare. Our experience working with states and federal policy makers also qualifies us to provide leadership of new cross-CERTs initiatives involving Medicaid agencies and complex, high-cost patients PUBLIC HEALTH RELEVANCE: Mental health conditions account for a substantial share of overall illness burden and health care expenditure, and substantially complicate the course and treatment of other medical disorders. The Center's work will address these critical issues, serving as a national observatory on the use and outcomes of mental health treatments in large, usual-care settings, incorporating strong partnerships with key stakeholders.