Program to improve care in complex chronic disease

描述(申请人提供)：这个为期5年的奖项的目的是加强首席研究员在复杂慢性病转化研究中以患者为导向的研究方面独特的多学科培训，并加强她指导下一代学者的能力。具体地说，有了这个奖项，调查员将：(1)扩大她在移动和基于网络的应用程序方面的内容专业知识，这些应用程序对翻译研究有用。(2)在慢性肾脏疾病患者中开发和试点一种新的网络支持的生活方式管理干预措施。(3)为从事以患者为中心的研究活动的受训者和初级教员提供指导，并从事与多发病患者的翻译研究有关的职业。(4)通过开发P30应用程序来支持多发病转化研究中心，使她的研究计划制度化。 公共卫生相关性：慢性病患者的数量正在增长，预计到2030年将达到1.71亿人，几乎一半的慢性病患者患有多种慢性病。然而，关于自我管理的文献主要来自于预防或人群中的经验工作，这些人患有简单的疾病，并采用针对单一行为的干预措施。该应用程序旨在进一步促进候选人在多发病方面的以患者为导向的翻译研究。该奖项将为申请者提供足够的保护时间来实现以下目标：(1)指导下一代研究人员，(2)在职业生涯中期进行转变，将基于网络的干预纳入她的研究，(3)开发和实施一项针对慢性肾病患者的基于网络的干预的试点研究，以及(4)开发P30应用程序，以使她与多病转化研究中心的研究计划制度化。

DESCRIPTION (provided by applicant): The purpose of this 5-year award is to build upon the unique multidisciplinary training of the principle investigator in patient-oriented research pertaining to translational research in complex chronic disease, and strengthen her ability to guide the next generation of scholars. Specifically, with this award the investigator will: (1) Expand her content expertise pertaining to mobile- and web-based applications useful for translational research. (2) Develop and pilot test a new web-supported lifestyle management intervention in those with chronic kidney disease. (3) Serve as a mentor for trainees and junior faculty members pursuing patient-oriented research activities and careers pertaining to translational research in those with multimorbidity. (4) Institutionalize her program of research by developing a P30 application to support a Center on Translational Research in Multimorbidity. PUBLIC HEALTH RELEVANCE: The number of people with chronic illness is growing and projected to reach 171 million by the year 2030, and almost 1/2 of those with a chronic disease have multiple chronic conditions. However, the literature on self-management has been derived mainly from empirical work in prevention or populations with uncomplicated disease and employ interventions that target a single behavior. This application is designed to further the candidate's patient-oriented translational research in multimorbidity. The award will provide the applicant with sufficient protected time to accomplish the following aims: (1) mentor the next generation of researchers, (2) engage in a mid-career shift to incorporate web-based interventions into her research, (3) develop and implement a pilot study using a web-based intervention in chronic kidney disease patients, and (4) develop a P30 application to institutionalize her research program with a Center for Translational Research in Multimorbidity.