Program to improve care in complex chronic disease

描述（由申请人提供）：这个为期5年的奖项的目的是建立在与复杂慢性病转化研究有关的以患者为导向的研究的主要研究者的独特多学科培训的基础上，并加强她指导下一代学者的能力。具体而言，通过该奖项，研究者将：（1）扩大她在移动的和基于网络的应用程序对翻译研究有用的内容专业知识。(2)在慢性肾脏疾病患者中开发和试点测试一种新的网络支持的生活方式管理干预。(3)担任学员和初级教师的导师，从事以患者为导向的研究活动和与多Morphis转化研究有关的职业。(4)通过开发一个P30应用程序来支持多学科转化研究中心，使她的研究计划制度化。 公共卫生相关性：慢性病患者的人数正在增加，预计到2030年将达到1.71亿，近1/2的慢性病患者患有多种慢性病。然而，关于自我管理的文献主要来自预防或患有简单疾病的人群的经验性工作，并采用针对单一行为的干预措施。这个应用程序的目的是进一步候选人的病人为导向的翻译研究多morphine。该奖项将为申请人提供足够的保护时间，以实现以下目标：（1）指导下一代研究人员，（2）从事职业生涯中期转变，将基于网络的干预纳入其研究，（3）在慢性肾病患者中使用基于网络的干预开发并实施试点研究，和（4）开发一个P30应用程序，使她的研究计划制度化，并在多个国家的翻译研究中心。

DESCRIPTION (provided by applicant): The purpose of this 5-year award is to build upon the unique multidisciplinary training of the principle investigator in patient-oriented research pertaining to translational research in complex chronic disease, and strengthen her ability to guide the next generation of scholars. Specifically, with this award the investigator will: (1) Expand her content expertise pertaining to mobile- and web-based applications useful for translational research. (2) Develop and pilot test a new web-supported lifestyle management intervention in those with chronic kidney disease. (3) Serve as a mentor for trainees and junior faculty members pursuing patient-oriented research activities and careers pertaining to translational research in those with multimorbidity. (4) Institutionalize her program of research by developing a P30 application to support a Center on Translational Research in Multimorbidity. PUBLIC HEALTH RELEVANCE: The number of people with chronic illness is growing and projected to reach 171 million by the year 2030, and almost 1/2 of those with a chronic disease have multiple chronic conditions. However, the literature on self-management has been derived mainly from empirical work in prevention or populations with uncomplicated disease and employ interventions that target a single behavior. This application is designed to further the candidate's patient-oriented translational research in multimorbidity. The award will provide the applicant with sufficient protected time to accomplish the following aims: (1) mentor the next generation of researchers, (2) engage in a mid-career shift to incorporate web-based interventions into her research, (3) develop and implement a pilot study using a web-based intervention in chronic kidney disease patients, and (4) develop a P30 application to institutionalize her research program with a Center for Translational Research in Multimorbidity.