7th International Conference on Unstable Microsatellites in Human Disease

描述（由申请人提供）：本申请为第七届不稳定微卫星与人类疾病国际会议（UMDH7）申请资金。2012年6月9日至14日，法国斯特拉斯堡附近的奥迪勒。以前的会议轮流在北欧/中欧和欧洲举行。UMHD7将汇集来自世界各地的顶尖科学家，讨论关于重复疾病的高影响力跨学科研究，目前已经确定了近40种重复疾病。会议的目的是通过将该领域的主要研究人员与广泛的专家代表聚集在一起，促进科学讨论和促进跨学科交流；临床医生、诊断学家、神经生物学家、病理学家、遗传学家和分子生物学家。会议关注该领域的最新进展，具体目标是：1)加强与重复扩张病相关的信息公开交流。这是不同领域的成员参加一个代表所有重复性疾病的会议的为数不多的机会之一。2)促进刺激和启动全球合作研究，以促进我们对与重复不稳定性相关的人类疾病的理解。该系列在成功交流与合作方面有着良好的记录，并鼓励了突破性研究。3)为初级研究人员提供机会，展示他们的工作，并与多个不同领域的顶尖科学家互动。我们的目标是通过一个深思熟虑和全面的计划吸引最优秀的年轻人，让他们有机会以海报和研讨会的形式展示自己的作品。我们的目标是创造一个包容和舒适的环境，让这些初级研究人员有机会公开交流思想，并与更资深的科学家互动。总之，我们已经开发了一个创新和前沿的科学项目，将强调重复疾病的致病和诱变机制的新兴主题，并利用这些知识体系进行治疗。会议包括直接从事重复障碍工作的演讲者以及可以从其他领域提供观点的演讲者。主讲人（Stephen Warren和Nahum Sonenberg）反映了我们的目标，即在一个通常无法获得的论坛上引入广泛的专业知识，为疾病的致病机制和各种治疗策略的研究提供信息。

DESCRIPTION (provided by applicant): This application requests funding for the 7th International Conference on Unstable Microsatellites in Human Disease (UMDH7) will be held at Mt. Ste. Odile, near Strasbourg France from June 9-14, 2012. The previous conferences have alternated between North/Central and European sites. UMHD7 will bring together top scientists from around the world to discuss high-impact, interdisciplinary research on Repeat Disorders, almost 40 have now been identified. The objective of the conference is to promote scientific discussion and facilitate interdisciplinary exchange by bringing leading researchers in the field together with a broad range of experts representing; clinicians, diagnosticians, neurobiologists, pathologists, geneticists and molecular biologists. Focusing on the most recent advances in the field, the specific aims of the conference are: 1) To enhance the open exchange of information related to repeat expansion diseases. This is one of the few opportunities members of different fields have to attend a conference that represents all of the repeat disorders. 2) To foster stimulation and initiation of global collaborative research to advance our understanding of human diseases related to repeat instability. The UMHD series has a proven track record of successful exchange and collaboration and has encouraged breakthrough research. 3) To provide junior investigators with an opportunity to present their work and interact with leading scientists in multiple and diverse fields. We aim to attract the best young minds using a well thought out and comprehensive program so that they have an opportunity to present their own work in both poster and seminar formats. We aim to make an inclusive and comfortable environment where these junior investigators have a chance to openly exchange ideas and interact with the more senior scientists. In summary, we have developed an innovative and cutting edge scientific program that will emphasize emerging themes in pathogenic and mutagenic mechanisms of the repeat disorders and harness these bodies of knowledge for therapeutic benefit. Sessions include speakers who directly work on repeat disorders as well as speakers who can provide perspectives from other fields. The keynote speakers (Stephen Warren and Nahum Sonenberg) reflect our goal to bring in broad expertise to inform studies into pathogenic mechanisms of disease and various treatment strategies in a forum that would not normally be available. PUBLIC HEALTH RELEVANCE: The 7th International Conference on Unstable Microsatellites in Human Disease will bring together researchers and clinicians to discuss cutting-edge information on disease mechanisms and therapeutic interventions for these devastating diseases. In addition, the format of the Conference and the funding sought herein will promote and ensure the attendance and enhanced education of junior scientists, including graduate students, postdoctoral fellows, and junior faculty.