7th International Conference on Unstable Microsatellites in Human Disease

描述(由申请人提供)：本申请申请资助第七届人类疾病不稳定微卫星国际会议(UMDH7)将在Mt.斯蒂。奥迪勒，法国斯特拉斯堡附近，2012年6月9日至14日。之前的会议轮流在北部/中部和欧洲地点举行。UMHD7将汇集来自世界各地的顶尖科学家，讨论针对重复疾病的高影响力、跨学科研究，目前已确定近40项。会议的目的是促进科学讨论和促进跨学科交流，将该领域的领先研究人员与代表临床医生、诊断专家、神经生物学家、病理学家、遗传学家和分子生物学家的广泛专家聚集在一起。会议侧重于该领域的最新进展，其具体目标是：1)加强与重复扩张性疾病有关的信息的公开交流。这是少数几个不同领域的成员有机会参加代表所有重复障碍的会议之一。2)促进刺激和启动全球合作研究，以促进我们对与重复不稳定相关的人类疾病的理解。UMHD系列在成功交流和合作方面有着良好的记录，并鼓励了突破性的研究。3)为初级研究人员提供机会介绍他们的工作，并与多个不同领域的顶尖科学家互动。我们的目标是通过一个深思熟虑和全面的计划来吸引最优秀的年轻人，这样他们就有机会以海报和研讨会的形式展示自己的作品。我们的目标是创造一个包容和舒适的环境，让这些初级调查人员有机会公开交流想法，并与更资深的科学家互动。总而言之，我们开发了一个创新和尖端的科学计划，将强调重复障碍的致病和突变机制中的新兴主题，并利用这些知识体系获得治疗效益。会议包括直接研究重复障碍的演讲者，以及可以从其他领域提供观点的演讲者。主旨发言人(Stephen Warren和Nahum Sonenberg)反映了我们的目标，即引入广泛的专业知识，在一个通常不会提供的论坛上为疾病致病机制和各种治疗策略的研究提供信息。 与公共卫生相关：第七届人类疾病不稳定微卫星国际会议将使研究人员和临床医生齐聚一堂，讨论有关疾病机制和针对这些毁灭性疾病的治疗干预措施的前沿信息。此外，会议的形式和在此寻求的资金将促进和确保初级科学家的出席和加强教育，包括研究生、博士后研究员和初级教员。

DESCRIPTION (provided by applicant): This application requests funding for the 7th International Conference on Unstable Microsatellites in Human Disease (UMDH7) will be held at Mt. Ste. Odile, near Strasbourg France from June 9-14, 2012. The previous conferences have alternated between North/Central and European sites. UMHD7 will bring together top scientists from around the world to discuss high-impact, interdisciplinary research on Repeat Disorders, almost 40 have now been identified. The objective of the conference is to promote scientific discussion and facilitate interdisciplinary exchange by bringing leading researchers in the field together with a broad range of experts representing; clinicians, diagnosticians, neurobiologists, pathologists, geneticists and molecular biologists. Focusing on the most recent advances in the field, the specific aims of the conference are: 1) To enhance the open exchange of information related to repeat expansion diseases. This is one of the few opportunities members of different fields have to attend a conference that represents all of the repeat disorders. 2) To foster stimulation and initiation of global collaborative research to advance our understanding of human diseases related to repeat instability. The UMHD series has a proven track record of successful exchange and collaboration and has encouraged breakthrough research. 3) To provide junior investigators with an opportunity to present their work and interact with leading scientists in multiple and diverse fields. We aim to attract the best young minds using a well thought out and comprehensive program so that they have an opportunity to present their own work in both poster and seminar formats. We aim to make an inclusive and comfortable environment where these junior investigators have a chance to openly exchange ideas and interact with the more senior scientists. In summary, we have developed an innovative and cutting edge scientific program that will emphasize emerging themes in pathogenic and mutagenic mechanisms of the repeat disorders and harness these bodies of knowledge for therapeutic benefit. Sessions include speakers who directly work on repeat disorders as well as speakers who can provide perspectives from other fields. The keynote speakers (Stephen Warren and Nahum Sonenberg) reflect our goal to bring in broad expertise to inform studies into pathogenic mechanisms of disease and various treatment strategies in a forum that would not normally be available. PUBLIC HEALTH RELEVANCE: The 7th International Conference on Unstable Microsatellites in Human Disease will bring together researchers and clinicians to discuss cutting-edge information on disease mechanisms and therapeutic interventions for these devastating diseases. In addition, the format of the Conference and the funding sought herein will promote and ensure the attendance and enhanced education of junior scientists, including graduate students, postdoctoral fellows, and junior faculty.