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CryoEM Core

CryoEM Core
冷冻电镜核心
批准号：
8528179
负责人：
Peijun Zhang
金额：
$45.7万
依托单位：
UNIVERSITY OF PITTSBURGH AT PITTSBURGH
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/8528179
关键词：
CapsidCharacteristicsClassificationCollaborationsComplexComputational algorithmComputer softwareCryoelectron MicroscopyFloridaHIVHeterogeneityIndividualMethodsMissionNegative StainingProteinsProtocols documentationSP1 geneServicesStaining methodStainsStructureparticleprotein complexreconstructionubiquitin-protein ligase

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中文摘要
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英文摘要
directed by Peijun Zhang, with collaborative effort from Hanspeter Winkler (Florida State U). Service Mission: The CryoEM Core will: 1) characterize structural features of HIV and host protein complexes by negative staining to determine their suitability for further structural study; 2) determine the structures of complexes/assemblies deemed suitable; 3) develop methods for single particle cryoEM and cryoET to analyze structural heterogeneity.
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Cryo EM/ET Core
Cryo EM/ET Core
Structure and function of membrane receptor signaling complex in bacterial chemot
Cryo-FIB processing of vitreous biological specimen for electron tomography
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