Statistics, Epidemiology, and Data Management Core

统计、流行病学和数据管理核心

• 批准号: 8374746
• 负责人: BRUCE LEVIN
• 金额: $ 34.59万
• 依托单位: NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-02-01 至 2013-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8374746
• 关键词: AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Behavior; Behavior Therapy; Behavioral; Behavioral Sciences; Chairperson; Characteristics; Clinical; Clinical Trials Data Monitoring Committees; Communities; Data; Data Analyses; Data Base Management; Data Collection; Data Quality; Developing Countries; Development; Discipline; Doctor of Medicine; Doctor of Philosophy; Ensure; Epidemic; Epidemiology; Faculty; Fostering; Future; Gender; Geographic Information Systems; Goals; Grant; Growth; HIV; HIV Infections; Individual; Infectious Disease Epidemiology; International; Intervention; Intervention Studies; Intervention Trial; Joints; Leadership; Marshal; Mental Health; Methods; Mission; Monitor; Observational Study; Online Systems; Performance; Positioning Attribute; Preparation; Prevention; Production; Productivity; Psychiatry; Public Health Schools; Publications; Randomized; Randomized Controlled Trials; Recommendation; Research; Research Design; Research Infrastructure; Research Personnel; Resolution; Resources; Risk; Role; Science; Senior Scientist; Sexuality; Social Behavior; Solutions; Specialist; Staging; Statistical Models; Strategic Planning; Structure; Technology; career; comparative; data management; design; distributed data; epidemiologic data; experience; high standard; improved; innovation; instrumentation; meetings; member; multi-site trial; randomized trial; relational database; response; skills; social; social organization; statistics; transmission process

The Statistics, Epidemiology, and Data Management Core (SED) will advance HIV research and improve the quality of proposals submitted by HIV Center-affiliated researchers by providing advice and assistance with state-of-the-art statistics, epidemiology, and data management. The Core will continue to serve as a center of excellence for the planning and design of investigator-initiated observational studies and behavioral interventions to reduce the risk of HIV infection on the individual, couple, group, and community levels. It will identify previously unrecognized statistical needs and study design improvements at the earliest planning stages in order to generate innovative solutions. The SED Core will meet the biostatistical, epidemiologic, and data management needs of Center-affiliated studies in a centralized and unified manner, consistent with modern principles of conduct of randomized controlled trials for behavioral intervention studies and observational methods for comparative or descriptive, nonexperimental studies. With its tripartite structure, the Core provides an interrelated network of talented specialists who are interdisciplinary and collaborate on all aspects of marshaling evidence: study design and instrumentation, anticipation and avoidance of bias, data management, statistical analysis and weighing of evidence, and interrelation with other disciplines to evaluate evidence and make causal inferences. The Statistics Component increases the likelihood that the randomized trials and observational studies will achieve their scientific goals through the application of good statistical principles and practices that minimize threats to validity. The biostatistical faculty and staff in the Core are highly experienced in collaborating with investigators in keeping studies on target and are pro-active in identifying and seeking resolutions to new statistical problems. The Epidemiology Component sits at the interface of the behavioral and biomedical sciences and thus is uniquely positioned to contribute to the articulation and refinement of research questions, to the selection of appropriate study designs, to the resolution of issues that arise in the field, and to the interpretation of the resulting data. The Data Management Component provides state-of-the-art management of research information, including forms production, relational database management and web-based research products. The integration of these skills and resources into one Core has led to a synergistic interaction of disciplines to identify and develop specific technical methods and products that will enhance the research productivity of the Center and support new and innovative research. The SED Core also organizes preparation for Performance, Safety & Monitoring Board meetings and coordinates responses to PSMB queries and recommendations.

统计、流行病学和数据管理核心 (SED) 将推进艾滋病毒研究并改进 艾滋病毒中心附属研究人员通过提供建议和提交的提案的质量 提供最先进的统计、流行病学和数据管理方面的协助。核心将继续 作为研究者发起的观察计划和设计的卓越中心 研究和行为干预，以降低个人、夫妇、群体感染艾滋病毒的风险， 和社区层面。它将确定以前未认识到的统计需求和研究设计 在最早的规划阶段进行改进，以产生创新的解决方案。 SED 核心 将满足中心附属研究的生物统计、流行病学和数据管理需求 集中统一的方式，符合现代随机对照的行为原则 行为干预研究的试验和比较或描述性、非实验性的观察方法 研究。凭借其三方结构，核心提供了一个相互关联的人才网络 跨学科专家在整理证据的各个方面进行协作：研究设计 和仪器、预期和避免偏差、数据管理、统计分析和 权衡证据，以及与其他学科的相互关系，以评估证据并做出因果关系 推论。统计部分增加了随机试验和 观察性研究将通过应用良好的统计原理来实现其科学目标 以及尽量减少对有效性的威胁的实践。核心的生物统计学教职人员都具有高度的专业知识。 在与研究人员合作保持研究目标方面具有丰富的经验，并且积极主动 识别新的统计问题并寻求解决方案。流行病学部分位于 行为科学和生物医学科学的交叉点，因此具有独特的地位，可以为 研究问题的阐明和细化，选择适当的研究设计， 解决现场出现的问题，并对结果数据进行解释。数据 管理组件提供最先进的研究信息管理，包括表格 生产、关系数据库管理和基于网络的研究产品。这些的整合 将技能和资源整合到一个核心中，导致了学科之间的协同互动，以识别和发展 将提高中心研究生产力的具体技术方法和产品 支持新的和创新的研究。 SED 核心还组织性能、安全方面的准备工作 & 监督委员会会议并协调对 PSMB 询问和建议的响应。