Regulation of Hormone Resistant Breast Cancer by IGF and Insulin System
Regulation of Hormone Resistant Breast Cancer by IGF and Insulin System
批准号:
8555338
负责人:
PAUL HALUSKA
金额:
$36.3万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2005
资助国家:
美国
项目状态:
已结题
起止时间:
2005-09-22 至 2016-08-31
关键词:
AdjuvantAffectApoptoticAromataseAromatase InhibitorsBindingBiological MarkersBiopsyBreast Cancer CellCell DeathClinicClinicalClinical ResearchCollectionCombined Modality TherapyCorrelative StudyDataDevelopmentDiseaseEndocrineEstradiolEstrogen ReceptorsEstrogen receptor positiveEstrogensExcisionFulvestrantGrowth FactorHormonalHormonesHumanIn VitroInsulinInsulin ReceptorInsulin-Like Growth Factor IIInsulin-Like-Growth Factor I ReceptorInvestigationLetrozoleLigandsMalignant NeoplasmsMammary NeoplasmsMediatingMediator of activation proteinMetabolicModelingMolecularMolecular ProfilingMonoclonal AntibodiesMonoclonal Antibody TherapyOutcomePatientsPharmaceutical PreparationsPhasePlayProtein IsoformsProteinsReceptor Protein-Tyrosine KinasesReceptor SignalingRecurrenceResistanceRoleSafetySerumSignal PathwaySignal TransductionSomatomedinsSystemTamoxifenTherapeutic EffectTissuesTranslatingType I InsulinTyrosine Kinase InhibitorUnited StatesWomanXenograft procedurebasedeprivationeffective therapyfetalhormone regulationhormone therapyin vitro Modelin vivoinhibitor/antagonistinsulin signalinginterestmalignant breast neoplasmnovelpre-clinicalpreventreceptorreceptor functionresearch clinical testingresearch studyresistance mechanismresponsesmall moleculetooltumor
中文摘要
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英文摘要
Both effective and tolerable, hormonal agents such as tamoxifen and aromatase inhibitors have had a
profound Impact on the treatment of estrogen receptor positive (ER
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(PQD5) Avatar-directed Treatment for Ovarian Cancer
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批准号:8682446
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项目类别:
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资助金额:$62.16万
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财政年份:2014
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负责人:PAUL HALUSKA
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依托单位:
Core D - Animal Models Core
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批准号:9333231
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项目类别:
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资助金额:$14.93万
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财政年份:2009
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负责人:PAUL HALUSKA
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依托单位:
Core D - Animal Models Core
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批准号:8932126
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项目类别:
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资助金额:$12.77万
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财政年份:2009
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负责人:PAUL HALUSKA
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依托单位:
Core D - Animal Models Core
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批准号:9149467
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项目类别:
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资助金额:$13.88万
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财政年份:2009
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负责人:PAUL HALUSKA
-
依托单位:
Core D - Animal Models Core
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批准号:9767677
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项目类别:
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资助金额:$18.13万
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财政年份:--
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负责人:PAUL HALUSKA
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依托单位:
海外基金