EASTERN COOPERATIVE ONCOLOGY GROUP
东方肿瘤合作组
基本信息
- 批准号:8304351
- 负责人:
- 金额:$ 37.65万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:1978
- 资助国家:美国
- 起止时间:1978-06-01 至 2014-02-28
- 项目状态:已结题
- 来源:
- 关键词:Abramson Cancer Center at the University of PennsylvaniaApplications GrantsAreaBedsCancer CenterCancer FamilyClinicalClinical InvestigatorClinical ResearchClinical TrialsColon CarcinomaCommitCommunitiesComprehensive Cancer CenterConduct Clinical TrialsData QualityDevelopmentDiffusionDisorder by SiteDrug IndustryEastern Cooperative Oncology GroupEligibility DeterminationEnsureEnvironmentEquipmentFacultyFinancial SupportFloorFundingGrantHandHematologyHospitalsHousingHuman ResourcesIndividualInpatientsInstitutesInstitutionIntensive Care UnitsKnowledgeLaboratoriesLeadLeadershipLeftMalignant NeoplasmsMalignant neoplasm of lungMalignant neoplasm of prostateMedical OncologyMedicineModalityModelingMonitorNational Cancer InstituteNursesOperative Surgical ProceduresOutpatientsPatient CarePatientsPennsylvaniaPhysiciansPlayPresbyterian ChurchPrincipal InvestigatorProgram DevelopmentProtocols documentationProtonsRadiation OncologyRadiation therapyRadiology SpecialtyRadiosurgeryRelative (related person)ResearchResearch InstituteResearch PersonnelResource SharingResourcesReview CommitteeRoleSiteSocietiesTechnologyTrainingUnited StatesUnited States National Institutes of HealthUniversitiesUniversity Hospitalsanticancer researchcancer research center directorcancer therapycostdata managementdrug developmentfallshuman subjectmalignant breast neoplasmmultidisciplinarymultimodalitynondrug therapyoncologypatient orientedpatient populationpopulation basedprogramsprotocol developmentsquare foot
项目摘要
DESCRIPTION (provided by applicant): This application is being submitted to continue the University of Pennsylvania's role as a main institution in the Eastern Cooperative Oncology Group beyond its 37 years of continuous particpation. The overarching objectives are to continue to serve as a scientific and administrative resource for the Group, to enter patients onto ECOG protocols, and to coordinate and support a large affiliate network. In the latter role, this application will support the diffusion of knowledge of clinical trials, assist in the proper conduct of clinical trials, and make these trials accessible to the broadest possible population of patients with cancer. Although the University of Pennsylvania has had an outstanding track record in all aspects of cooperative group activities, including accrual, administrative and scientific input and data quality, the specific aims of the proposal for the next six years are to: 1. continue to enhance accrual in all disease site and modalities, beyong our current particpation, particularly in breast and lung cancers. 2. increase physician, nurse, and data management participation in Group activities, including protocol development. 3. attract new affilaites through the Abramson Cancer Center network, allowing for enhanced availability for clinical trials participation in the larger community The relevance of this project to the ultimate cure of cancer is self-evident. Cooperative groups are the main force outside of the pharmaceutical industry dedicated to the definitve tesing of new treatments, studying not just new drug development but also non-drug treatment, such as radiation therapy and surgery, for which there would be nooter funding. These cooperative group activities, and the specific involvement of the University of Pennsylvania, represent the chief way in which the ultimate model of multimodal, collaborative patient care can be performed. The main ECOG grant describes in detail the very specific way in which clinical trials have led to
RELEVANCE: Malignancies remain an enormous burden for individuals in the United States and for society as a whole. Without public support of clinical trials, both by financial support as well as participation in clinical trials, progress will not be made. If left in private hands, large areas of cancer treatment will go unexplored, denying patients the possibility of progress.
描述(由申请人提供):正在提交申请,以继续宾夕法尼亚大学作为东部合作肿瘤学集团的主要机构的角色,超过其连续37年的参与度。总体目标是继续作为该小组的科学和行政资源,将患者输入ECOG协议,并协调和支持大型会员网络。在后者的角色中,该应用将支持临床试验知识的扩散,有助于适当进行临床试验,并使这些试验可用于最广泛的癌症患者人群。尽管宾夕法尼亚大学在合作团体活动的各个方面都有出色的往绩,包括应计,行政和科学意见和数据质量,但未来六年的提案的具体目的是:1。继续增强所有疾病现场的应计值,在所有疾病现场,我们目前的肉欲,尤其是母乳和Lung Cancers。 2。增加医师,护士和数据管理参与包括协议开发在内的小组活动。 3.通过艾布拉姆森癌症中心网络吸引新的会员,从而增强了临床试验参与较大社区的可用性,该项目与癌症的最终治疗的相关性是不言而喻的。合作群体是专门用于确定新疗法的制药行业之外的主要力量,不仅研究新药开发,而且还研究非药物治疗,例如放射治疗和手术,为此提供了Nooter资助。这些合作小组活动以及宾夕法尼亚大学的特定参与代表了可以进行多模式,协作患者护理的最终模型的主要方式。主要的ECOG赠款详细描述了临床试验导致的非常具体的方式
相关性:在美国和整个社会中,恶性肿瘤仍然是一个巨大的负担。没有公众对临床试验的支持,无论是通过财务支持还是参与临床试验,都不会取得进展。如果私下手中,大部分癌症治疗将无法探索,否认患者的进展可能性。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Selina M Luger其他文献
Single Cell Transcriptomic Analysis of B-Cell Acute Lymphoblastic Leukemia (B-ALL) Reveals Correlation between Leukemia Cell State, Genetic Alterations and Clinical Outcome
- DOI:
10.1182/blood-2023-190180 - 发表时间:
2023-11-02 - 期刊:
- 影响因子:
- 作者:
Ilaria Iacobucci;Andy G.X. Zeng;Qingsong Gao;Laura Garcia Prat;Pradyumna Baviskar;Sayyam Shah;Alexander Murison;Veronique Voisin;Colin Bailey;Matthew Lear;Anjali S. Advani;Selina M Luger;Elisabeth Paietta;Wendy Stock;John E. Dick;Charles G. Mullighan - 通讯作者:
Charles G. Mullighan
Older Adults with Acute Myeloid Leukemia (AML) Experience Improvement in Health-Related Quality of Life (HRQoL) Scores with Intensive Therapy: Prospective Study from ECOG-ACRIN (EA) E2906 Phase 3 Trial
- DOI:
10.1182/blood-2023-189734 - 发表时间:
2023-11-02 - 期刊:
- 影响因子:
- 作者:
James M. Foran;Li Chen;Selina M Luger;Zhuoxin Sun;Heidi Klepin;David F. Claxton;Hillard M. Lazarus;Jacob M. Rowe;Jessica K. Altman;Aref Al-Kali;Hong Zheng;Keith W Pratz;Edward R. Broun;Bayard L Powell;Kristen M. O'Dwyer;Yishai Ofran;John E. Godwin;Mark R. Litzow;Martin S. Tallman;Lynne Wagner - 通讯作者:
Lynne Wagner
Comparing Cairo Bishop and Howard Criteria for Identifying Clinically Meaningful Tumor Lysis Syndrome Among Acute Myeloid Leukemia Patients Treated with Venetoclax and Hypomethylating Agents: A Single Center Experience
- DOI:
10.1182/blood-2023-186978 - 发表时间:
2023-11-02 - 期刊:
- 影响因子:
- 作者:
Margaret Rowe;Daria V Babushok;Martin Carroll;Alison Carulli;Noelle V. Frey;Saar Gill;Elizabeth O Hexner;Rebecca Hirsh;Nasheed Hossain;Catherine Lai;Alison W Loren;Selina M Luger;Ivan Maillard;Shannon R McCurdy;Andrew H Matthews;Mary Ellen Martin;Vikram R Paralkar;Alexander Perl;David L. Porter;Keith W Pratz - 通讯作者:
Keith W Pratz
Evolving Racial/Ethnic Disparities in AML Survival in the Novel Therapy Era: Real-World Evidence of Improved Survival in Older Patients with the Largest Improvement in Non-Hispanic Black Patients
- DOI:
10.1182/blood-2023-180185 - 发表时间:
2023-11-02 - 期刊:
- 影响因子:
- 作者:
Xin Wang;Phyllis Gimotty;Andrew H Matthews;Ronac Mamtani;Selina M Luger;Elizabeth O Hexner;Daria V Babushok;Shannon R McCurdy;Noelle V. Frey;Ximena Jordan Bruno;David L. Porter;Saar Gill;Mary Ellen Martin;Vikram R Paralkar;Ivan Maillard;Alison W Loren;Alexander Perl;Keith W Pratz;Kelly D. Getz;Catherine Lai - 通讯作者:
Catherine Lai
Hypomethylating Agents Are Associated with High Rates of Hematologic Toxicity in Patients with Secondary MDS/AML That Develops after Acquired Aplastic Anemia
- DOI:
10.1182/blood-2023-179383 - 发表时间:
2023-11-02 - 期刊:
- 影响因子:
- 作者:
Matthew P Connor;Neeharika Prathapa;Noelle V. Frey;Saar Gill;Elizabeth O Hexner;Ximena Jordan Bruno;Catherine Lai;Alison W Loren;Selina M Luger;Andrew H Matthews;Shannon R McCurdy;Alexander Perl;David L. Porter;Arlene Zeringue;Joseph H. Oved;Timothy S Olson;Keith W Pratz;Daria V Babushok - 通讯作者:
Daria V Babushok
Selina M Luger的其他文献
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{{ truncateString('Selina M Luger', 18)}}的其他基金
C-MYB ANTISENSE OLIGODEOXYNUCLEOTIDE IN CHRONIC MYELOGENOUS LEUKEMIA PATIENTS
C-MYB 反义寡脱氧核苷酸在慢性粒细胞白血病患者中的应用
- 批准号:
6565773 - 财政年份:2001
- 资助金额:
$ 37.65万 - 项目类别:
AUTOLOGOUS BONE MARROW TRANSPLANTATION: C-MYB ANTISENSE OLIGODEOXYNUCLEOTIDE
自体骨髓移植:C-MYB 反义寡脱氧核苷酸
- 批准号:
6565777 - 财政年份:2001
- 资助金额:
$ 37.65万 - 项目类别:
C-MYB ANTISENSE OLIGODEOXYNUCLEOTIDE IN CHRONIC MYELOGENOUS LEUKEMIA PATIENTS
C-MYB 反义寡脱氧核苷酸在慢性粒细胞白血病患者中的应用
- 批准号:
6468023 - 财政年份:2000
- 资助金额:
$ 37.65万 - 项目类别:
AUTOLOGOUS BONE MARROW TRANSPLANTATION: C-MYB ANTISENSE OLIGODEOXYNUCLEOTIDE
自体骨髓移植:C-MYB 反义寡脱氧核苷酸
- 批准号:
6468027 - 财政年份:2000
- 资助金额:
$ 37.65万 - 项目类别:
PURGING OF LEUKEMIC BONE MARROW WITH ANTISENSE DNA
用反义 DNA 清除白血病骨髓
- 批准号:
2085207 - 财政年份:1993
- 资助金额:
$ 37.65万 - 项目类别:
PURGING OF LEUKEMIC BONE MARROW WITH ANTISENSE DNA
用反义 DNA 清除白血病骨髓
- 批准号:
3034746 - 财政年份:1992
- 资助金额:
$ 37.65万 - 项目类别:
相似海外基金
Translational Research Cancer Centers Consortium Annual Meeting
转化研究癌症中心联盟年会
- 批准号:
8319055 - 财政年份:2012
- 资助金额:
$ 37.65万 - 项目类别: