14th Annual Midwest DNA Repair Symposium

第 14 届年度中西部 DNA 修复研讨会

• 批准号: 8319116
• 负责人: PAUL R ANDREASSEN
• 金额: $ 0.6万
• 依托单位: UNIVERSITY OF CINCINNATI
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-04-01 至 2013-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8319116
• 关键词: Area; Cancer Detection; Collaborations; Communities; DNA Damage; DNA Repair; DNA Repair Pathway; Defect; Detection; Development; Funding; Genome Stability; Genomic Instability; Genomics; Growth; Institution; Laboratory Research; Lead; Malignant Neoplasms; Medical center; Medicine; Mutation; Outcome; Participant; Pathway interactions; Pediatric Hospitals; Peripheral; Postdoctoral Fellow; Reagent; Regulation; Research; Research Personnel; Resources; Scientist; Secure; Students; Translational Research; Travel; Universities; Work; cancer diagnosis; cancer therapy; carcinogenesis; career development; chemotherapeutic agent; college; graduate student; interest; lectures; meetings; new technology; novel strategies; peer; posters; programs; repaired; success; symposium; tumorigenesis

DESCRIPTION (provided by applicant): The overall objective of this proposal is to secure funding to support the 14th Annual Midwest DNA repair Symposium (AMDRS) to be held May 19-20, 2012 at the University of Cincinnati, Cincinnati, OH, with Cincinnati Children's Hospital Medical Center (CCHMC) as co-host. AMDRS is a regional conference that brings together researchers from across the Midwest who study DNA damage/repair and how it relates to cancer. DNA repair pathways are required to maintain genomic stability with loss of repair pathways leading to genomic mutations and tumorigenesis. DNA repair and regulation of repair pathways can also influence the effect of chemotherapeutic agents. The AMDRS has a high quality scientific program but is affordable and convenient. Consequently, it attracts a diverse array of researchers from across the Midwest. It provides an excellent opportunity for students, post-doctoral fellows and young PIs to present their work and to interact with senior investigators. It is enjoyed by senior PIs because of the scientific quality and the unique opportunity to interact with colleagues from neighboring institutions. It also attracts PIs who are interested in DNA damage/repair but who work in peripheral areas and would not normally attend a national DNA repair meeting. The program will include keynote lectures from prominent scientists, four sessions of short talks and two poster sessions. There will be a focus on new technology/approaches relevant to the intersection between DNA damage/repair and cancer development, detection and treatment. The aims of the conference are: To provide a venue for DNA repair researchers, principally from the Midwestern states, to present recent progress in their research programs, to network with other investigators and to form new collaborations. 2. To provide a venue for graduate students, postdoctoral fellows and young investigators to present their research among peers and to interact with leaders in the field. 3. To provide an affordable but high quality scientific meeting that allows participation from the diverse constituents of the DNA repair community. PUBLIC HEALTH RELEVANCE: This proposal seeks funding to support a regional conference focusing on DNA repair and its relevance to cancer development, detection and treatment. The conference will attract a diverse group of researchers from across the Midwest and hence will help disseminate information that will enhance our understanding of the relationship between DNA damage/repair and tumorigenesis and how this relationship can be exploited in cancer diagnosis and treatment.

描述（由申请人提供）：本提案的总体目标是确保获得资金，以支持将于2012年5月19日至20日在辛辛那提的辛辛那提大学举行的第14届年度中西部DNA修复研讨会（AMDRS），辛辛那提儿童医院医疗中心（CCHMC）将作为联合主办单位。AMDRS是一个区域性会议，汇集了来自中西部的研究人员，他们研究DNA损伤/修复及其与癌症的关系。DNA修复途径是维持基因组稳定性所必需的，修复途径的缺失导致基因组突变和肿瘤发生。DNA修复和修复途径的调节也可以影响化疗剂的效果。AMDRS有一个高质量的科学计划，但价格实惠，方便。因此，它吸引了来自整个中西部的各种各样的研究人员。它为学生，博士后研究员和年轻的PI提供了一个很好的机会来展示他们的工作，并与高级研究人员互动。它是由高级PI享受，因为科学质量和独特的机会，与来自邻近机构的同事互动。它也吸引了PI谁是 对DNA损伤/修复感兴趣，但在周边地区工作，通常不会参加国家DNA修复会议。该计划将包括著名科学家的主题演讲，四个简短的会谈和两个海报会议。将重点关注与DNA损伤/修复和癌症发展，检测和治疗之间的交叉相关的新技术/方法。会议的目的是：为主要来自中西部各州的DNA修复研究人员提供一个场所，介绍他们研究计划的最新进展，与其他研究人员建立网络并形成新的合作。2.为研究生，博士后研究员和年轻的研究人员提供一个场所，在同行中展示他们的研究，并与该领域的领导者互动。3.提供一个负担得起的，但高质量的科学会议，允许从DNA修复社区的不同组成部分的参与。 公共卫生相关性：该提案寻求资金，以支持一个区域会议，重点是DNA修复及其与癌症发展、检测和治疗的相关性。会议将吸引来自中西部的不同研究人员，因此将有助于传播信息，提高我们对DNA损伤/修复与肿瘤发生之间关系的理解，以及如何在癌症诊断和治疗中利用这种关系。