UMB Non-Human Primate Core

优化利用非人类灵长类动物进行生物防御和新出现的病原体研究需要一个设施 动物被安置在适当的生物围栏中，研究人员在 传染病研究和疫苗开发所需的方法。非人灵长类 巴尔的摩马里兰大学(NHP)Core将提供最先进的动物生物安全水平 (ABSL)2和3个使用非人类灵长类进行生物防御研究的设施。目前，我们的设施支持 旨在开发炭疽、天花和沙门氏菌疫苗的项目。这些 项目使用NHP作为研究疾病发病机制和测试疫苗效力的动物模型，并 安全。我们的设施完全支持ABSL-2和3级的生物危害研究，并满足所有NIH/CDC的要求 指导方针。我们的专家人员将为计划使用NHP的调查人员提供咨询服务 生物危害研究的核心。我们将提供我们在利用NHP方面的丰富经验，用于 各种疾控中心A、B和C类药物的发病机制研究和疫苗开发。因此， NHP核心将是支持旨在开发创新技术的提案的一个非常重要的组成部分 针对生物恐怖分子的治疗学。

Optimal utilization of nonhuman primates for biodefense and emerging pathogens research requires a facility where animals are housed in appropriate biocontainment and research personnel experienced in the methodologies required for infectious disease research and vaccine development. The non-human primate (NHP) Core at the University of Maryland, Baltimore will provide state-of-the-art animal biosafety levels (ABSL) 2 and 3 facilities for biodefense research using nonhuman primates. Currently, our facilities support projects aimed at developing vaccines against anthrax, smallpox and S. dysenteriae 1 vaccines. These projects use NHPs as animal models for studying disease pathogenesis and testing vaccine efficacy and safety. Our facilities fully support biohazard research at ABSL-2 and 3 levels and meet all NIH/CDC guidelines. Our expert personnel will provide consultation services to investigators planning to use the NHP core for biohazard studies. We will make available our extensive experience in the utilization of NHPs for pathogenesis research and vaccine development for various CDC category A, B and C agents. Hence, the NHP core will be a very important component to support proposals aimed at developing innovative therapeutics against bioterrorism agents.