UMB Non-Human Primate Core
UMB Non-Human Primate Core
批准号:
8233383
负责人:
LOUIS James DE TOLLA
金额:
$10.14万
依托单位国家:
美国
项目类别:
财政年份:
2011
资助国家:
美国
项目状态:
已结题
起止时间:
2011-03-01 至 2014-02-28
关键词:
Animal HousingAnimal ModelAnimalsAnthrax diseaseAreaBaltimoreBiohazardous SubstanceBiomedical ResearchBioterrorismCategoriesCenters for Disease Control and Prevention (U.S.)ClinicalConsultationsCore FacilityDiseaseEmerging Communicable DiseasesGuidelinesHuman ResourcesInfectious AgentInfectious Diseases ResearchMarylandMedicalMethodologyPathogenesisResearchResearch PersonnelResearch SupportServicesShigella dysenteriaeSmallpoxTestingTherapeuticUnited States National Institutes of HealthUniversitiesVaccinesVeterinary Medicinebiodefensedrug efficacyexperienceinnovationmeetingsnonhuman primatepathogenresearch and developmentvaccine developmentvaccine efficacyvaccine safety
中文摘要
最佳利用非人灵长类动物进行生物防御和新出现的病原体研究需要一个设施
如果动物被圈养在适当的生物隔离中,
传染病研究和疫苗开发所需的方法。非人灵长类
(NHP)位于巴尔的摩的马里兰州大学的核心将提供最先进的动物生物安全水平
(ABSL)2和3设施使用非人类灵长类动物的生物防御研究。目前,我们的设施支持
这些项目旨在开发针对炭疽、天花和沙门氏菌的疫苗。大肠杆菌1型疫苗。这些
项目使用NHP作为动物模型,研究疾病发病机制和测试疫苗效力,
安全为代价的我们的设施完全支持ABSL-2和3级的生物危害研究,并符合所有NIH/CDC
指南我们的专家人员将为计划使用NHP的研究人员提供咨询服务
生物危害研究的核心。我们将提供我们在利用NHP方面的丰富经验,
针对各种CDC类别A、B和C剂的致病机理研究和疫苗开发。所以
NHP核心将是一个非常重要的组成部分,以支持旨在发展创新的建议,
生物恐怖制剂的治疗方法。
英文摘要
Optimal utilization of nonhuman primates for biodefense and emerging pathogens research requires a facility
where animals are housed in appropriate biocontainment and research personnel experienced in the
methodologies required for infectious disease research and vaccine development. The non-human primate
(NHP) Core at the University of Maryland, Baltimore will provide state-of-the-art animal biosafety levels
(ABSL) 2 and 3 facilities for biodefense research using nonhuman primates. Currently, our facilities support
projects aimed at developing vaccines against anthrax, smallpox and S. dysenteriae 1 vaccines. These
projects use NHPs as animal models for studying disease pathogenesis and testing vaccine efficacy and
safety. Our facilities fully support biohazard research at ABSL-2 and 3 levels and meet all NIH/CDC
guidelines. Our expert personnel will provide consultation services to investigators planning to use the NHP
core for biohazard studies. We will make available our extensive experience in the utilization of NHPs for
pathogenesis research and vaccine development for various CDC category A, B and C agents. Hence, the
NHP core will be a very important component to support proposals aimed at developing innovative
therapeutics against bioterrorism agents.
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专著(0)
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会议论文
UMB Non-Human Primate Core
-
批准号:7672164
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项目类别:
-
资助金额:$10.52万
-
财政年份:2009
-
负责人:LOUIS James DE TOLLA
-
依托单位:
Non Human Primate Core and the S. dysenteriae Vaccine Development Study - MARGE
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批准号:7679316
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项目类别:
-
资助金额:$6.61万
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财政年份:2008
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负责人:LOUIS James DE TOLLA
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依托单位:
XENOGEN IVIS-200 SMALL ANIMAL IMAGING SYSTEM: INFECTIOUS DISEASE
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批准号:7335168
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项目类别:
-
资助金额:$14.06万
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财政年份:2006
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负责人:LOUIS James DE TOLLA
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依托单位:
Xenogen IVIS-200 small animal imaging system
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批准号:7040274
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项目类别:
-
资助金额:$28.12万
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财政年份:2006
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负责人:LOUIS James DE TOLLA
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依托单位:
XENOGEN IVIS-200 SMALL ANIMAL IMAGING SYSTEM: CANCER
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批准号:7335167
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项目类别:
-
资助金额:$14.06万
-
财政年份:2006
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负责人:LOUIS James DE TOLLA
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依托单位:
DEVELOPING AND IMPROVING INSTITUTIONAL ANIMAL RESOURCES
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批准号:6190445
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项目类别:
-
资助金额:$11.09万
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财政年份:2000
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负责人:LOUIS James DE TOLLA
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依托单位:
DEVELOPING AND IMPROVING INSTITUTIONAL ANIMAL RESOURCES
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批准号:2284066
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项目类别:
-
资助金额:$9.99万
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财政年份:1993
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负责人:LOUIS James DE TOLLA
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依托单位:
DEVELOPING AND IMPROVING INSTITUTIONAL ANIMAL RESOURCES
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批准号:2283682
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项目类别:
-
资助金额:$7.46万
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财政年份:1992
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负责人:LOUIS James DE TOLLA
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依托单位:
DEVELOPING AND IMPROVING INSTITUTIONAL ANIMAL RESOURCES
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批准号:2283382
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项目类别:
-
资助金额:$8.22万
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财政年份:1991
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负责人:LOUIS James DE TOLLA
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依托单位:
IMPROVING INSTITUTIONAL ANIMAL CARE FACILITIES
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批准号:3059065
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项目类别:
-
资助金额:$16.78万
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财政年份:1990
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负责人:LOUIS James DE TOLLA
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依托单位:
UMB Non-Human Primate Core
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批准号:8442379
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项目类别:
-
资助金额:$5.67万
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财政年份:--
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负责人:LOUIS James DE TOLLA
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依托单位:
UMB Non-Human Primate Core
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批准号:8375168
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项目类别:
-
资助金额:$6.55万
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财政年份:--
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负责人:LOUIS James DE TOLLA
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依托单位:
UMB Non-Human Primate Core
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批准号:8037622
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项目类别:
-
资助金额:$11.12万
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财政年份:--
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负责人:LOUIS James DE TOLLA
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依托单位:
海外基金