Interdisciplinary Training in Genes and the Environment

描述（由申请人提供） 在基因和环境跨学科培训计划在公共卫生（HSPH）的哈佛学院将解决训练有素的科学家谁有一个理解，并致力于，在分子和环境暴露生物学，统计和计算方法的交叉前沿研究的迫切需要。该培训计划将涉及30名有成就和经验丰富的多学科教师的积极参与，包括环境卫生科学家，分子生物学家，分子流行病学家，计算生物学家，生物统计学家和生物信息学家。我们提出的培训计划的两个相互关联的目标是：培养真正的合作伙伴能够追求的方法学研究是由动机，并有助于解决，在人类环境暴露和遗传易感性复杂疾病的研究中出现的困难的分析问题;为了鼓励跨学科研究，特别是在遗传学和各种“组学”方面，这些“组学”产生于描述实验室和人口科学中与环境暴露有关的生物活动的新方法。受训人员将是HSPH环境卫生、流行病学、生物统计学、遗传学和复杂疾病系的博士前学生和博士后研究员，这些系将共同管理赠款。该方案建议为3名博士预科生提供初步支助，第2年增加2名学员，第3年增加3名学员，使每年共有8名博士预科生进入该方案（第3-8年）。该计划还计划每年支持一名博士后研究员的培训。这些博士后学员将拥有与暴露生物学/环境健康科学或基因组学/蛋白质组学计算领域相关的高级学位（博士，医学博士，医学博士或其他博士学位），并将对交叉培训研究经验特别感兴趣。在基因与环境计划跨学科培训的所有学员将提供一个优秀的机会，成为基因组学，环境健康科学和定量方法的同等熟练，以实现人类基因和环境的跨学科研究的领导作用，与服务于公共卫生利益的最终目标制定有效的疾病预防和干预策略。

DESCRIPTION (provided by applicant) The Interdisciplinary Training in Genes and the Environment program at the Harvard School of Public Health (HSPH) will address the critical need for well-trained scientists who have an understanding of, and commitment to, cutting-edge research at the intersection of molecular and environmental exposure biology, and statistical and computational methods. The training program will involve active participation by 30 accomplished and experienced multidisciplinary faculty members, including environmental health scientists, molecular biologists, molecular epidemiologists, computational biologists, biostatisticians and bioinformaticians. The two interrelated goals of our proposed training program are: To train true collaborative partners able to pursue methodological research that is motivated by, and helps to solve, difficult analytic issues that arise in studies of human environmental exposures and genetic susceptibility to complex diseases; To encourage interdisciplinary research, especially in genetics and the various "omics" arising from new methodologies for characterizing biological activity associated with environmental exposures in laboratory and population sciences. Trainees will be pre-doctoral students and post-doctoral fellows at HSPH in the Departments of Environmental Health, Epidemiology, Biostatistics, and Genetics and Complex Diseases, which will jointly administer the grant. The program proposes initial support for 3 pre-doctoral students with 2 additional trainees in year 2 and 3 additional trainees in year 3 to bring an annual total of 8 pre-doctoral students into the program (year 3-8). The program also plans to support training of one post-doctoral fellow per year. These post-doctoral trainees will have an advanced degree (PhD, MD, MD-PhD or other doctoral degree) relevant to exposure biology/environmental health sciences or computational areas of genomics/proteomics and will have a specific interest in cross-training research experience. All trainees in the Interdisciplinary Training in Genes and Environment program will be provided an outstanding opportunity to become equally skilled in genomics, environmental health sciences and quantitative methods in order to attain leadership roles in interdisciplinary studies of human genes and the environment, with the ultimate goal of serving public health interests in developing effective disease prevention and intervention strategies.