How the intestinal microenvironment controls propulsion and mixing of food in the gut: parallel transduction pathways

肠道微环境如何控制肠道内食物的推进和混合：平行转导途径

• 批准号: nhmrc : 566642
• 负责人: Dr Evan Thomas
• 金额: $ 77.17万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/intestinal-microenvironment-controls-transduction-pathways/101225
• 关键词: How; intestinal; microenvironment; controls; propulsion

This project will identify the mechanisms that control the mixing of food with digestive juices, the absoprtion of nutrients from the gut to the blood stream and the excretion of waste. Disruption of these processes causes significant health problems and is associated with normal aging and many diseases. We will identify nutrients and other food components (eg spices) that switch gut from mixing to propulsion and hence identify targets to treat disorders of gut movement.

该项目将确定控制食物与消化液混合、营养物质从肠道吸收到血流以及废物排泄的机制。这些过程的破坏会导致严重的健康问题，并与正常衰老和许多疾病有关。我们将确定将肠道从混合转变为推进的营养素和其他食物成分（例如香料），从而确定治疗肠道运动障碍的目标。