Growing Right Onto Wellness (GROW): Changing Early Childhood BMI Trajectories

健康成长 (GROW)：改变幼儿期 BMI 轨迹

• 批准号: 8305496
• 负责人: Shari Barkin
• 金额: $ 220.96万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-20 至 2017-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8305496
• 关键词: Address; Adherence; Adolescent; Adult; Affect; Age; Alleles; Behavior; Biolectric Impedance; Child; Childhood; Communities; County; Data; Diet; Educational Curriculum; Energy Intake; Family; Focus Groups; Food Preferences; Genetic; Genetic Predisposition to Disease; Genetic Risk; Goals; Habits; Health; Intervention; Life Style; Low income; Macronutrients Nutrition; Maintenance; Measures; Monitor; Morbidity - disease rate; Neighborhoods; Nursery Schools; Obesity; Outcome; Overweight; Parents; Pattern; Pediatrics; Phase; Physical activity; Pilot Projects; Population; Preschool Child; Principal Investigator; Problem Solving; Public Health; Questionnaires; Randomized; Randomized Controlled Trials; Recommendation; Recreation; Relative (related person); Research; Risk; Saliva; Schools; Single Nucleotide Polymorphism; Social Network; System; Testing; Time; Weight; Wellness Program; actigraphy; base; early childhood; genetic risk factor; group intervention; high risk; high risk parents; improved; indexing; innovation; interest; intervention effect; lifestyle intervention; literacy; mortality; nutrition; obesity prevention; prevent; primary outcome; programs; sedentary; skills; success; tool; waist circumference

DESCRIPTION (provided by applicant): Food preferences and activity habits set in early childhood can profoundly influence lifelong trajectories for Body l\/lass Index (BMI) and health. Specifically, rapid BMI gain in early childhood has been established to affect adulthood mortality and morbidity. Unfortunately, the longer such unhealthy patterns are in place, the more difficult it can be to reverse them. Therefore, healthy lifestyle interventions targeted at children as early as preschool 'have enormous potential to affect lifelong health. Furthermore, nutrition and activity patterns are determined not only at the child level, but within the family and the community. Building on the success of an existing partnership between Vanderbilt Pediatrics and Metro Parks and Recreation in Nashville, TN, we will conduct and evaluate an intervention intended to prevent obesity in preschoolers in an approach that affects multiple levels of risk and is both family-based and community centered. Prior to launching a large randomized controlled trial (RCT), formative research (focus groups and pilot studies) will be conducted to refine the intervention components. In the RCT, 600 parent-preschool children dyads from low income neighborhoods will be randomly assigned to one of two conditions. In the intervention condition, groups of parent-child dyads will participate in an empirically tested, literacy-sensitive, skills building curriculum to improve: 1) caloric intake with appropriate macronutrients, and 2) routine physical activity for both parent and child. The intervention condition will occur in community centers and utilize tools including goal setting, self-monitoring, and problem solving. In the control condition parent-child dyad groups will receive a literacy promotion/school success curriculum. Both conditions will have 90-minute sessions in: 1) an initiation phase (weekly for 3 months); 2) a maintenance phase (biweekly for 6 months); and 3) a sustainability phase (monthly for 27 months). The primary outcome of interest will be early childhood BMI trajectories measured at multiple time points over the three year RCT. Additional measures collected throughout the study from children and parents will include: bioelectrical impedance; waist circumference; actigraphy; 3-day diet recalls; questionnaires; social network data; and saliva to assess a genetic risk score associated with obesity. RELEVANCE: Pediatric obesity prevention must occur in preschool given that 60% of oven/weight preschoolers will go on to become overweight adolescents. By conducting and testing trials in public community centers, exportable interventions could result allowing for a macro-level system change to address this expanding public health crisis.

描述（由申请人提供）：