基因组筛选以确定新型应激诱导癌症化疗药物-猫眼课题宝

基因组筛选以确定新型应激诱导癌症化疗药物

批准号：

8182154

负责人：

Andrew Michael Fribley

金额：

$24.9万

依托单位：

WAYNE STATE UNIVERSITY

依托单位国家：

美国

项目类别：

财政年份：

2011

资助国家：

美国

项目状态：

已结题

起止时间：

2011-02-01 至 2014-01-31

来源：

https://reporter.nih.gov/project-details/8182154

关键词：

Academia Address Adjuvant Therapy Affect Apoptosis Apoptotic Biological Assay Breathing Carcinoma Caring Cell Death Cell Line Cells Chemicals Cisplatin Development Disease Dose Drug Interactions Drug Kinetics Enzymes Funding Genetic Programming Genomics Glean Growth Head and Neck Neoplasms Head and Neck Squamous Cell Carcinoma Head and neck structure Human In Vitro Individual Instruction Investigation Laboratories Lead Libraries Luciferases Malignant Epithelial Cell Mediating Metabolic Metabolism Michigan Molecular Target Neoplasm Metastasis Operative Surgical Procedures P-Glycoprotein Pain Pathway interactions Patients Pharmaceutical Chemistry Pharmaceutical Preparations Pharmacologic Substance Phase Physiological Probability Proteasome Inhibition Proteins Pump Radiation Radiation therapy Reporter Reporting Resistance Screening procedure Sensitivity and Specificity Series Signal Transduction Stress Structure Structure of thyroid parafollicular cell Survival Rate Technology Testing Tumor Burden Universities Work Xenograft Model Xenograft procedure analog arm base cellular targeting chemotherapy cost effective cytotoxic drug clearance drug development drug metabolism high throughput screening improved in vivo insight killings mouth squamous cell carcinoma neoplastic cell new therapeutic target novel protein folding research study response small molecule small molecule libraries success therapeutic development treatment strategy tumor

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批准号：

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项目类别：
资助金额：

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海外基金