NF-kB 的新亚基赋予基因调控特异性-猫眼课题宝

NF-kB 的新亚基赋予基因调控特异性

批准号：

8202679

负责人：

Fengyi Wan

金额：

$24.15万

依托单位：

JOHNS HOPKINS UNIVERSITY

依托单位国家：

美国

项目类别：

财政年份：

2011

资助国家：

美国

项目状态：

已结题

起止时间：

2011-01-05 至 2013-12-31

来源：

https://reporter.nih.gov/project-details/8202679

关键词：

20 year old Address Affinity Affinity Chromatography Apoptosis Award B-Lymphocytes Binding Binding Sites Biochemical Biochemical Pathway Biological Assay Cell Line Cell Nucleus Cell physiology Cells Chronic Complex Cytoplasm DNA DNA Binding DNA Sequence Data Disease Electrophoretic Mobility Shift Assay Environment Evolution Faculty Gene Expression Gene Expression Profile Gene Expression Regulation Gene Targeting Genes Genetic Transcription Goals Heterogeneous-Nuclear Ribonucleoprotein K Human IL2RA gene Immune response Immunoglobulins In Vitro Inflammation Inflammatory Ink Instruction Interleukin-2 Intervention KH Domain Knowledge Length Ligands Light Link Malignant Neoplasms Mammalian Cell Maps Mass Spectrum Analysis Mediating Mentorship Microarray Analysis Modeling Molecular Mus NF-kappa B Nuclear Extract Pathway interactions Peptides Peripheral Blood Lymphocyte Phase Physiological Physiological Processes Play Positioning Attribute Proteins Public Health Recombinants Regulation Regulator Genes Reporter Genes Research Research Personnel Role Sequence Analysis Signal Pathway Signal Transduction Site Specificity Superantigens T-Cell Activation T-Cell Lymphoma T-Lymphocyte TNFRSF5 gene Tertiary Protein Structure Therapeutic Therapeutic Intervention Time Transcriptional Regulation Universities Viral Genes Work base cancer therapy career development cell growth cell type chromatin immunoprecipitation design dimer drug discovery empowered experience improved in vivo in vivo Model inhibitor/antagonist innovation insight intercellular communication model design new therapeutic target novel p65 reconstitution research study response ribosomal protein S3 skills small molecule synaptotagmin I transcription factor

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会议论文

Targeting the Sam68-stimulated PARP1 activation for cancer treatment

批准号：

10058388
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资助金额：

$45.12万
财政年份：

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负责人：

Fengyi Wan
依托单位：

JOHNS HOPKINS UNIVERSITY

Targeting the Sam68-stimulated PARP1 activation for cancer treatment

批准号：

10401422
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Targeting the Sam68-stimulated PARP1 activation for cancer treatment

批准号：

10163145
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PARylation in genotoxic stress-induced NF-kB activation

批准号：

9262264
项目类别：
资助金额：

$36.46万
财政年份：

2015
负责人：

Fengyi Wan
依托单位：

JOHNS HOPKINS UNIVERSITY

PARylation in genotoxic stress-induced NF-kB activation Supplement

批准号：

9169988
项目类别：
资助金额：

$2.64万
财政年份：

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负责人：

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依托单位：

JOHNS HOPKINS UNIVERSITY

PARylation in genotoxic stress-induced NF-kB activation Supplement for Research on Sex/Gender Influences

批准号：

9431267
项目类别：
资助金额：

$10.46万
财政年份：

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负责人：

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依托单位：

JOHNS HOPKINS UNIVERSITY

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批准号：

8885067
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资助金额：

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财政年份：

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依托单位：

JOHNS HOPKINS UNIVERSITY

Novel Subunit of NF-kB Confers Gene Regulatory Specificity

批准号：

8403734
项目类别：
资助金额：

$22.7万
财政年份：

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负责人：

Fengyi Wan
依托单位：

JOHNS HOPKINS UNIVERSITY

Novel Subunit of NF-kB Confers Gene Regulatory Specificity

批准号：

8210985
项目类别：
资助金额：

$24.15万
财政年份：

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负责人：

Fengyi Wan
依托单位：

JOHNS HOPKINS UNIVERSITY

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