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The PAR-6/aPKC Polarity Complex in Synaptic Assembly and Function

The PAR-6/aPKC Polarity Complex in Synaptic Assembly and Function
突触组装和功能中的 PAR-6/aPKC 极性复合体
批准号：
8203101
负责人：
Huaye Zhang
金额：
$24.9万
依托单位：
UNIV OF MED/DENT NJ-R W JOHNSON MED SCH
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
项目状态：
已结题
起止时间：
2009-05-01 至 2013-12-31
来源：
https://reporter.nih.gov/project-details/8203101
关键词：
ActinsAddressAffectAlzheimer&aposs DiseaseAxonBehavioralBrainCell divisionCell surfaceCellsClinicalComplexDataDendritic SpinesEndocytosisEnvironmentEpithelialExcitatory SynapseGlutamate ReceptorGlutamatesGoalsGuanine Nucleotide Exchange FactorsGuanosine Triphosphate PhosphohydrolasesInstructionKnockout MiceMaintenanceMediatingMemoryMemory impairmentMental RetardationMentorsMolecularMonomeric GTP-Binding ProteinsMorphogenesisNervous System PhysiologyNeurodegenerative DisordersNeuronsPARD6A genePathway interactionsPhasePhosphorylationPoly(ADP-ribose) PolymerasesProcessProteinsRecyclingRegulationResearch ProposalsRoleSchizophreniaSignal PathwaySignal TransductionStructureSurfaceSynapsesSynaptic TransmissionSynaptic plasticityTestingTranslatingVertebral columnVesiclebasebrain cellcognitive functionin vivomigrationnervous system disordernovelresponsesynaptic functiontransmission process

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