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Mechanisms of Spliceosome Assembly and Splice Site Selection

Mechanisms of Spliceosome Assembly and Splice Site Selection
剪接体组装和剪接位点选择的机制
批准号：
8308082
负责人：
Aaron Andrew Hoskins
金额：
$24.9万
依托单位：
UNIVERSITY OF WISCONSIN-MADISON
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
项目状态：
已结题
起止时间：
2008-12-01 至 2014-07-31
来源：
https://reporter.nih.gov/project-details/8308082
关键词：
3&apos Splice Site5&apos Splice SiteATP HydrolysisATP phosphohydrolaseAchievementAddressAffectAffinityAlternative SplicingAwardBase PairingBindingBinding ProteinsBiochemicalBiological AssayBiological ModelsBiologyBoxingCell ExtractsCellsChemicalsChemistryCollaborationsComplexCouplingCustomCystic FibrosisDiseaseDissectionDissociationDistalEnsureEnzymesEventExonsFluorescenceFundingGene Expression RegulationGeneticGoalsGrowthHealthHela CellsHumanHuman BiologyIndividualInstructionIntronsKineticsLaboratoriesLengthLigationLocationMalignant NeoplasmsMeasurementMedicineMessenger RNAMethodologyMethodsMolecular ConformationMutagenesisMutationNuclear ExtractOrganismPathway interactionsPhasePlasmidsPlayPositioning AttributeProbabilityProcessProductionProtein BindingProtein ConformationProtein IsoformsProteinsPublicationsRNARNA Cap-Binding ProteinsRNA CapsRNA ProcessingRNA SplicingReactionReading FramesRecruitment ActivityRegulationReportingResearchResearch PersonnelResistanceRetinitis PigmentosaRoleSaccharomyces cerevisiaeSchemeScienceSignal TransductionSiteSmall Nuclear RNASmall Nuclear RibonucleoproteinsSpectrum AnalysisSpliceosome Assembly PathwaySpliceosomesStagingStructureSurfaceSystemThermodynamicsTranscriptU1 Small Nuclear RibonucleoproteinU1 small nuclear RNAU2 Small Nuclear RibonucleoproteinU2 small nuclear RNAWorkYeast Model SystemYeastsbasecollegefluorescence microscopefluorophoregenetic regulatory proteinhuman diseaseimprovedinsightinterestmRNA Precursormutantpreventprogramsprotein functionprotein protein interactionresearch studysingle moleculesingle-molecule FRETstemsuccesstool

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Administrative Supplement: Mechanisms of Spliceosome Assembly and Regulation
  • 批准号：
    10169637
  • 项目类别：
  • 资助金额：
    $0.58万
  • 财政年份：
    2020
  • 负责人：
    Aaron Andrew Hoskins
  • 依托单位：
    UNIVERSITY OF WISCONSIN-MADISON
Administrative Supplement: Mechanisms of Spliceosome Assembly and Regulation
  • 批准号：
    10378361
  • 项目类别：
  • 资助金额：
    $16.03万
  • 财政年份：
    2020
  • 负责人：
    Aaron Andrew Hoskins
  • 依托单位：
    UNIVERSITY OF WISCONSIN-MADISON
Mechanisms of Spliceosome Assembly and Regulation
  • 批准号：
    10608952
  • 项目类别：
  • 资助金额：
    $37.31万
  • 财政年份：
    2020
  • 负责人：
    Aaron Andrew Hoskins
  • 依托单位：
    UNIVERSITY OF WISCONSIN-MADISON
Mechanisms of Spliceosome Assembly and Regulation
  • 批准号：
    10393514
  • 项目类别：
  • 资助金额：
    $37.31万
  • 财政年份：
    2020
  • 负责人：
    Aaron Andrew Hoskins
  • 依托单位：
    UNIVERSITY OF WISCONSIN-MADISON
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