Protocol Specific

协议特定

• 批准号: 8250423
• 负责人: HOWARD H. BAILEY
• 金额: $ 11.7万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2013-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8250423
• 关键词: Clinical; Clinical Research; Clinical Research Protocols; Clinical Trials Network; Comprehensive Cancer Center; Data; Databases; Development; Funding; Grant; Lead; Methods; Monitor; Nursing Research; Peer Review; Performance; Phase; Pilot Projects; Protocols documentation; Recording of previous events; Reporting; Research; Research Personnel; Research Priority; Research Support; Staging; Translational Research; Wisconsin; base; data management; flexibility; innovation; member; novel; oncology; programs; research study; translational study

The UWCCC proposes to have available for its members Protocol Specific Research support for pilot clinical/translational research studies that would benefit from timely funding. The UWCCC has a long history of funding pilot studies that have led to more timely clinical research and NCI funding. The UWCCC has funded 15 (8 of these ongoing or recently initiated) early phase pilot clinical studies over the last grant period with an accrual of 173 subjects. Efficient accrual to UWCCC-supported studies is enhanced by the UWCCC-supported statewide clinical trials network (Wisconsin Oncology Network). This method of support allows investigators with emerging ideas or promising initial pilot data to apply for the support of a research nurse and data manager to conduct high priority, innovative, feasibility and early stage institutional clinical research protocols. Proposals will be requested twice yearly and will undergo peer-review (under the direction of Associate Directors H. Bailey and P. Sondel) with selection based on scientific merit, need for Protocol Specific Research funding, potential to lead to NCI funding, and UWCCC research priorities. Once selected, protocols receive research nurse/data management support from this mechanism and all the necessary developmental and regulatory support via the Oncore database for UWCCC-required monitoring and reporting.

UWCCC提议为其成员提供针对试点的特定议定书研究支持 将受益于及时资助的临床/转化性研究。UWCCC有着悠久的历史 为先导研究提供资金，从而导致更及时的临床研究和NCI资金。UWCCC已经 在上一次资助期间，资助了15项(其中8项正在进行或最近启动)早期试点临床研究 应计173名受试者。UWCCC支持的研究的有效收益通过 UWCCC支持的全州临床试验网络(威斯康星州肿瘤学网络)。这种支持方法 允许有新想法或有希望的初步试验数据的调查人员申请支持研究 护士和数据经理进行高优先级、创新性、可行性和早期机构临床 研究方案。建议书将每年征求两次，并将接受同行审查(根据 副主任H.Bailey和P.Sondel的指导)根据科学价值进行选择，需要 议定书特定的研究资助，可能导致NCI资助，以及UWCCC研究优先事项。一次 选定方案后，研究护士/数据管理支持从该机制和所有 通过OnCore数据库为UWCCC所需的监测提供必要的发展和监管支持 和报道。