EXERCISE INTENSITY EFFECTS ON WEIGHT AND FAT LOSS IN MIDDLE AGED ADULTS

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 子项目的主要研究者可能是由其他来源提供的， 包括其它NIH来源。 为子项目列出的总成本可能 表示子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 在美国，肥胖症正在达到流行病的程度，但是有一小部分人能够通过热量限制和运动的结合来减肥并保持减肥。已经描述了在久坐条件下进食的激素和生理控制。不太为人所知的是，运动过程中代谢燃料的消耗如何影响这些控制。更好地理解代谢能量消耗对饥饿的影响以及运动强度对食欲抑制的影响具有重要的理论和应用意义。假设在高强度运动期间和之后，食欲会受到抑制;与久坐状态相比，低强度运动后的饥饿评级不会增加。具体的目的是比较如何平等的能量赤字，通过不同强度的运动引起的影响心理生理评级的食欲，以及荷尔蒙和代谢反射，久坐不动的状态，超重，年轻女性。这项研究的结果将为继续研究提供更多信息，包括喂养的激素和代谢控制及其与运动的关系。此外，研究结果可以扩展对能量调节的理论理解，并为个人改善减肥策略提供见解。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Obesity in the United States is reaching epidemic proportions, however there are a small number of individuals who are able to lose weight and maintain the loss through a combination of caloric restriction and exercise. Hormonal and physiological controls of feeding under sedentary conditions have been described. What is less well known is how the expenditure of metabolic fuels during exercise affects these controls. A better understanding of the impact of the metabolic energy expenditure on hunger and of exercise intensity on appetite suppression is of great theoretical and applied importance. It is hypothesize that during and following high-intensity exercise appetite will be suppressed; and hunger ratings will not be increased following low-intensity exercise compared to a sedentary state. The specific aim is to compare how equal energy deficit incurred through exercise of varying intensities affects psychophysical ratings of appetite, as well as hormonal and metabolic reflexes, to a sedentary state, in overweight, young women. The findings from this study will provide additional information for continued work involving hormonal and metabolic controls of feeding and their relation to exercise. Additionally, results could extend theoretical understanding of energy regulation and provide insight for improved weight-loss strategies for individuals.