PROTEOMICS CORE

蛋白质组学核心

• 批准号: 8360050
• 负责人: JOHN B SHABB
• 金额: $ 16.28万
• 依托单位: UNIVERSITY OF NORTH DAKOTA
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8360050
• 关键词: Biomedical Research; Communities; Core Facility; Environment; Fees; Funding; Gel; Grant; Health; Image Analysis; Laboratories; Learning; Mass Spectrum Analysis; National Center for Research Resources; North Dakota; Postdoctoral Fellow; Principal Investigator; Proteins; Proteomics; Research; Research Infrastructure; Research Personnel; Research Project Grants; Research Support; Resources; Services; Source; Students; Technology; Training; Two-Dimensional Gel Electrophoresis; United States National Institutes of Health; biomedical scientist; cost; experience; graduate student; operation; two-dimensional

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The major responsibility of the Proteomics Core Facility is to support the research efforts of the INBRE investigators and the research community of the state of North Dakota. The Proteomics Core Facility will consist of an established mass spectrometry laboratory and a protein separation laboratory. The core facility will be directed by Dr. John Shabb who has extensive experience in protein mass spectrometry and proteomics. The core facility manager will be responsible for day-to-day operation of the facility. The core facility will offer the following services at moderate fees: protein separation by two-dimensional gel electrophoresis (2D-PAGE), image analysis of 2D-gels, and protein identification and structural characterization of the separated proteins by mass spectrometry. In addition to the services, the facility will offer educational training courses to undergraduate students, graduate students and post-doctoral fellows within the state. The training courses will include protein separation by 2D-PAGE, 2D-gel image analysis and protein identification by mass spectrometry. Thus, the Proteomics Core Facility will provide opportunities to biomedical scientists and students in North Dakota to employ the cutting edge technologies of proteomics into their research projects as well as to students to learn this important technology in the current biomedical research.

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 蛋白质组学核心基金的主要责任是支持INBRE研究人员和北达科他州研究界的研究努力。蛋白质组学核心设施将由一个已建立的质谱学实验室和一个蛋白质分离实验室组成。核心设施将由约翰·沙布博士领导，他在蛋白质质谱学和蛋白质组学方面拥有丰富的经验。核心设施经理将负责设施的日常运营。核心设施将以适中的费用提供以下服务：通过二维凝胶电泳(2D-PAGE)分离蛋白质、2D-凝胶的图像分析，以及通过质谱学对分离的蛋白质进行蛋白质鉴定和结构表征。除了这些服务，该设施还将为该州的本科生、研究生和博士后研究员提供教育培训课程。培训课程将包括2D-PAGE蛋白质分离、2D-Gel图像分析和质谱仪鉴定蛋白质。因此，蛋白质组学核心基金将为北达科他州的生物医学科学家和学生提供机会，将蛋白质组学的尖端技术应用于他们的研究项目，并让学生在当前的生物医学研究中学习这一重要技术。