Recruiting and Retaining Young Adults in Behavioral Weight Loss Treatment

招募和留住年轻人进行行为减肥治疗

• 批准号: 8241143
• 负责人: Jessica Gokee LaRose
• 金额: $ 5.91万
• 依托单位: MIRIAM HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-03-05 至 2012-09-03
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8241143
• 关键词: Address; Adult; Aftercare; Age; Alcohols; Area; Behavior Therapy; Behavioral; Behavioral Risk Factor Surveillance System; Body Weight decreased; Climacteric; Clinic; Clinical; Data; Data Analyses; Development; Eating; Employment; Enrollment; Environment; Focus Groups; Foundations; Future; Goals; Health; Hospitals; Individual; Intervention; Interview; Knowledge; Life; Longevity; Maintenance; Mentored Patient-Oriented Research Career Development Award; Mentors; Methodology; Methods; Mind; Newsletter; Obesity; Online Systems; Overweight; Participant; Phase; Population; Protocols documentation; Public Health; Qualifying; Qualitative Research; Randomized; Randomized Clinical Trials; Recruitment Activity; Research; Research Ethics; Research Methodology; Research Personnel; Research Training; Resources; Risk Factors; Sampling; Schedule; Series; Testing; Time; Training; Treatment Protocols; United States; Weight Gain; Weight maintenance regimen; Wing; Woman; Work; age group; arm; base; cardiovascular risk factor; career; college; design; effective therapy; experience; fast food; high risk; high school; improved; medical schools; meetings; men; novel marker; pandemic disease; patient oriented research; programs; residence; sex; skills; social; standard care; symposium; treatment program; weight gain prevention; young adult

DESCRIPTION (provided by applicant): The goal of this Mentored Patient-Oriented Research Career Award (K23) is to allow Dr. Gokee-LaRose to become an independent investigator focused on developing interventions to target modifiable CVD risk factors during the transition into young adulthood. This training plan, through didactic and direct mentored training experiences, will allow her to develop skills and expertise in: 1) design and conduct of randomized clinical trials (with an emphasis on obesity); 2) qualitative research methods, which will enable her to effectively tailor programs for young adults; 3) increased knowledge of CVD risk factors with relevance to young adults and methodology used to assess novel markers in RCTs; and 4) research ethics and the advanced statistical skills needed to analyze data resulting from RCTs. The resources at the Miriam Hospital/ Brown Medical School and close contact with her expert mentor team (Drs. Wing, Jelalian, Morrow, Lewis and Fava) will provide her with the ideal environment to achieve her training and research goals. Young adults between 18 and 25 are at particularly high risk for weight gain and obesity; yet, they are under-represented in standard programs and little is known about how best to recruit and/or retain this group in treatment. Our pilot data indicates significant weight losses can be achieved through a brief, clinic-based program with young adults, and maintained in the short-term. The goal of this proposal is twofold: 1) to conduct formative work aimed at improving recruitment and retention efforts with this age group, and 2) to conduct a randomized clinical trial to test the feasibility and preliminary efficacy of three different approaches to longer-term weight control. In Phase 1, 80 overweight or obese men and women ages 18-25 will participate in focus groups to address recruitment, retention and barriers to treatment. In Phase 2, a new sample of 90 participants will be enrolled in a brief, 10-week BWL program and then randomized to one of three maintenance arms through 12 months. Contact schedule and delivery format will be determined in part by Phase 1; the three arms will be continued face-to-face, a newsletter control, or an alternative form of continued contact. Assessments will take place at baseline, 10 weeks, 6 and 12 months.

描述（由申请人提供）： 这个指导以患者为导向的研究职业奖（K23）的目标是让Gokee-LaRose博士成为一名独立的研究者，专注于开发干预措施，以针对在过渡到年轻成年期期间可改变的CVD风险因素。该培训计划，通过教学和直接指导的培训经验，将使她能够发展以下方面的技能和专业知识：1）随机临床试验的设计和实施（重点是肥胖）; 2）定性研究方法，这将使她能够有效地为年轻人量身定制计划; 3）增加了对年轻人CVD危险因素的认识，以及RCT中用于评估新标志物的方法; 4）研究伦理和先进的统计技术需要分析数据从随机对照试验。米里亚姆医院/布朗医学院的资源以及与她的专家导师团队（Wing，Jelalian，Morrow，刘易斯和Fava博士）的密切联系将为她提供理想的环境，以实现她的培训和研究目标。18至25岁的年轻人体重增加和肥胖的风险特别高;然而，他们在标准计划中的代表性不足，并且对如何最好地招募和/或保留这一群体的治疗知之甚少。我们的试点数据表明，通过一个简短的，以诊所为基础的计划，可以实现显着的体重减轻，并在短期内保持。该提案的目标是双重的：1）进行旨在改善该年龄组招募和保留工作的形成性工作，2）进行随机临床试验，以测试三种不同方法的可行性和初步疗效，以长期控制体重。在第一阶段，80名18-25岁的超重或肥胖男性和女性将参加焦点小组，以解决招募，保留和治疗障碍。在第2阶段，90名参与者的新样本将入组一个简短的10周BWL项目，然后随机分配到三个维持组之一，持续12个月。联系时间表和交付格式将部分由第一阶段确定;三个武器将继续面对面，通讯控制，或继续接触的替代形式。将在基线、10周、6和12个月时进行评估。