TAS::75 0893::TAS RENEWABLE CAPTURES FOR ADDICTION-RELEVANT PROTEINS

TAS::75 0893::TAS 可再生捕获成瘾相关蛋白质

• 批准号: 8432390
• 负责人: XIAOMIN FAN
• 金额: $ 1.45万
• 依托单位: AVANTGEN, INC.
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-30 至 2012-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8432390
• 关键词: Affinity; Antibodies; Antigens; Contracts; Data Reporting; Genes; Human; Length; Libraries; National Institute of Drug Abuse; Neurosciences; Outcome; Phase; Proteins; Proteomics; Specificity; Technology; Work; Yeasts; addiction; commercialization; cost effective; interest

The overall objective of the proposed scope of work for this Phase II contract is to leverage AvantGen's proprietary yeast display technology and synthetic human antibody library to isolate renewable capture agents against neuroscience proteins of interest in a more rapid, cost effective-manner. A successful outcome of this Phase II will generate panels of antibodies that are well suited for proteomics.

该第二阶段合同的拟议工作范围的总体目标是利用AvantGen专有的酵母展示技术和合成人抗体库，以更快速、更具成本效益的方式分离可再生捕获剂，以对抗感兴趣的神经科学蛋白。 第二阶段的成功结果将产生非常适合蛋白质组学的抗体组。