How the lateral habenula integrates behavioral and autonomic functions: the VTA dopamine connection

外侧缰核如何整合行为和自主功能：VTA 多巴胺连接

• 批准号: nhmrc : GNT1101677
• 负责人: Dr Youichirou Ootsuka
• 金额: $ 81.99万
• 依托单位: Flinders University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/lateral-habenula-integrates-dopamine-connection/1346169
• 关键词: How; lateral; habenula; integrates; behavioral

When adverse events occur, the lateral habenula, an old brain nucleus, helps calculate the wisest corrective action by contributing to the “brake” that controls the brain’s dopamine reward system. Our research will show how the lateral habenula links corrective changes in behavior with coordinated changes in temperature. Understanding this link will greatly contribute to understanding the brain mechanisms that regulate our physiology during stressful situations and as part of mental illness.

当不良事件发生时，外侧缰核，一个古老的脑核，通过控制大脑多巴胺奖励系统的“刹车”来帮助计算最明智的纠正措施。我们的研究将展示外侧缰如何将行为的纠正变化与温度的协调变化联系起来。理解这种联系将极大地有助于理解在压力情况下调节我们生理的大脑机制，以及精神疾病的一部分。