2012 International Meeting on the Molecular Biology of Hepatitis B Viruses

2012年乙型肝炎病毒分子生物学国际会议

• 批准号: 8312807
• 负责人: JOHN L CASEY
• 金额: $ 0.5万
• 依托单位: HEPATITIS B FOUNDATION
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-06-01 至 2013-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8312807
• 关键词: Address; Animal Model; Antiviral Agents; Antiviral Therapy; Basic Science; Biochemistry; Biology; Biomedical Research; Cellular biology; Church; Communities; Development; Diabetes Mellitus; Digestive System Disorders; Discipline; Disease; Educational workshop; Financial Support; Foundations; Fund Raising; Funding; Gene Expression; Goals; Grant; Hepatitis B; Hepatitis B Virus; Hepatitis Delta Virus; Home environment; Immunity; Immunology; Infection; Institutes; International; Joints; Kidney Diseases; Knowledge; Light; Malignant Neoplasms; Minority; Mission; Modality; Molecular Biology; National Cancer Institute; National Institute of Allergy and Infectious Disease; National Institute of General Medical Sciences; Oral; Pathogenesis; Population; Postdoctoral Fellow; Primary carcinoma of the liver cells; RNA Editing; Regulatory Element; Research Personnel; Schedule; Schools; Scientist; Senior Scientist; Structure; Therapeutic; Time; Travel; Underrepresented Minority; United States National Institutes of Health; Universities; Vaccines; Viral; Virus; Virus Shedding; college; cost; gene therapy; graduate student; interest; lecturer; meetings; new therapeutic target; pathogen; posters; prophylactic; protein expression; vector; virology; virus host interaction

DESCRIPTION (provided by applicant): Project Summary This proposal is a request for funding to support the travel expenses for young scientists to attend and participate in the 2012 International Meeting on the Molecular Biology of Hepatitis B Viruses, scheduled for Sept. 23 - 26, 2012 at the University of Oxford Examination Schools and Christ Church College, Oxford, UK. This meeting is the only forum that gathers the international community of researchers that focus on the hepatitis B virus (HBV) and the closely associated hepatitis delta virus (HDV). Approximately 25% of the world's population has been infected by HBV. Unfortunately, despite the availability of prophylactic vaccines, many new infections occur worldwide, mostly because of underutilization of the vaccine due to cost and other issues. Moreover, for the approximately 360 million people already chronically infected with HBV (approximately 15 million of whom are co-infected with HDV), the vaccine is of no therapeutic value. As a result, between 0.5 and 1 million people die of HBV/HDV every year worldwide. It is therefore imperative that basic research and the scientific exchange among those studying HBV/HDV continue, and the annual HBV meeting represents the venue at which this can occur. The 2012 meeting will uphold and enhance the traditional format and exchange with interaction and dialogue presented in 9 oral scientific sessions, 2 poster sessions as well as less structured "networking" time. A special focus of this meeting will be on virus-host interactions, with a particular emphasis on cell biology, antiviral immunity, and new therapeutic targets. This will be facilitated by three keynote addresses and a special workshop. As in the past, great effort has been made to minimize the cost of the meeting. Furthermore, the Hepatitis B Foundation has made a strong commitment to support this meeting since 2005, in terms of providing a permanent home for organizing the meeting and making its staff available for organizing the meeting and publicizing it, especially to universities with large numbers of underrepresented minorities. In order to allow the participation of junior and minority investigators, support from the NIH to help defray the meeting costs of junior scientists is requested. PUBLIC HEALTH RELEVANCE: Project Narrative The 2012 Molecular Biology of Hepatitis B Viruses Meeting is the next scheduled meeting in an annual series that has been held continuously since 1985. This is the only definitive meeting that brings together basic scientists in the field of hepatitis B virus (HBV) and hepatitis D virus (HDV) from throughout the world. HBV continues to be a major global and US public health problem with more than 360 million individuals chronically infected worldwide and with an annual rate of up to one million deaths due to HBV and HBV/HDV-induced liver failure, cirrhosis, and hepatocellular carcinoma. The meeting is a critical and internationally well recognized platform for continued exchange of information in basic research on HBV and HDV infections.

描述（由申请人提供）：项目摘要本提案是一项资助年轻科学家出席和参加2012年国际B型肝炎病毒分子生物学会议的差旅费申请，该会议定于2012年9月12日在纽约举行。23 - 26，2012年在牛津大学考试学校和基督教堂学院，牛津，英国。本次会议是唯一的论坛，聚集了国际社会的研究人员，专注于B型肝炎病毒（HBV）和密切相关的丁型肝炎病毒（HDV）。世界上大约有25%的人口感染了HBV。不幸的是，尽管预防性疫苗的可用性，许多新的感染发生在世界各地，主要是因为疫苗的利用不足，由于成本和其他问题。此外，对于已经慢性感染HBV的约3.6亿人（其中约1500万人合并感染HDV），疫苗没有治疗价值。因此，全世界每年有50万至100万人死于HBV/HDV。因此，HBV/HDV研究者之间的基础研究和科学交流必须继续下去，而年度HBV会议是实现这一目标的场所。2012年会议将坚持和加强传统的形式和交流，在9次口头科学会议、2次海报会议以及结构较少的“网络”时间中进行互动和对话。本次会议的一个特别重点将是病毒-宿主相互作用，特别强调细胞生物学，抗病毒免疫和新的治疗靶点。这将通过三个主题来促进 演讲和一个特别的研讨会。同过去一样，为尽量减少会议费用作出了巨大努力。此外，B型肝炎基金会自2005年以来一直坚定地承诺支持这次会议，为组织会议提供一个永久的场所，并提供工作人员组织会议和宣传会议，特别是 有大量少数民族代表不足的大学。为了让初级和少数民族研究人员参与，国家卫生研究院的支持，以帮助支付会议 要求支付初级科学家的费用。 公共卫生相关性：2012年B型肝炎病毒分子生物学会议是自1985年以来连续举行的年度系列会议中的下一次预定会议。这是唯一一次汇集了来自世界各地的B型肝炎病毒（HBV）和丁型肝炎病毒（HDV）领域的基础科学家的权威会议。HBV仍然是全球和美国的主要公共卫生问题，全世界有超过3.6亿人慢性感染，每年有多达100万人死于HBV和HBV/HDV诱导的肝衰竭、肝硬化和肝细胞癌。该会议是一个重要的和国际公认的平台，在HBV和HDV感染的基础研究中继续交流信息。