Cancer Research Network Across Health Care Systems

描述（由申请人提供）：NIH路线图和NCI战略计划反复呼吁医疗保健系统更多地参与研究。提供从预防到缓解的全面护理的综合交付系统可以解决在许多其他环境中无法回答的关于癌症预防和控制的关键研究问题。具有内部研究能力的医疗保健系统联盟为研究癌症预防和护理政策和模式的变化创造了前所未有的机会。认识到这一潜力，国家癌症研究所于1997年发布了一份申请书，以“促进NCI赞助的癌症预防研究的进行......检测[and]通过卫生保健提供系统之间的合作进行“治疗”。作为回应，一组HMO（最初有10名合作者，在拟议的申请中有13名合作者）组成了HMO癌症研究网络（CRN），其总体目标是通过识别影响结果的个人，提供者，系统和治疗因素的研究来进行提高癌症预防和治疗有效性的研究。我们在这里提出了一个研究基础设施和一系列项目，利用独特的方面和贡献的网络的交付系统。拟议中的癌症研究网络包括四个核心，五个项目，以及在社区环境中翻译癌症护理创新的研究重点。CRN基础设施通过一组丰富的、相互连接的共享资源来支持我们的总体目标，这些项目共同利用CRN的地理多样性及其复杂的自动化数据功能。社区癌症网络计划旨在找出社区健康护理系统如何能以最佳方式回应已登记的成员：1）确保他们获得正确的癌症预防服务; 2）设计易于理解和使用的癌症预防信息; 3）为癌症患者提供有效和符合成本效益的治疗;（4）全面回应病人的生理及心理社会需要。CRN的研究将很容易适用于整个医疗保健环境，并将有助于癌症护理质量的整体改善。

DESCRIPTION (provided by applicant): The NIH Roadmap and NCI strategic plans repeatedly invoke the need for greater involvement of healthcare systems in research. Integrated delivery systems, which provide comprehensive care from prevention to palliation, can address key research questions about cancer prevention and control that cannot be answered in many other settings. A consortium of healthcare systems with internal research capabilities creates an unprecedented opportunity to study variations in policy and patterns of cancer prevention and care. In recognition of this potential, the National Cancer Institute issued a Request for Applications in 1997 to "facilitate the conduct of NCI sponsored research on cancer prevention...detection... [and] treatment" through collaboration among health care delivery systems. In response a group of HMOs (10 collaborators initially, and 13 in the proposed application), formed the HMO Cancer Research Network (CRN), whose overall objective is to conduct research that improves the effectiveness of cancer prevention and treatment through research that identifies individual, provider, system and treatment factors that affect outcomes. We propose herein a research infrastructure and array of projects that capitalize on the unique facets and contributions of a network of delivery systems. The proposed Cancer Research Network consists of four cores, five projects, and a research emphasis on translation of cancer care innovations in community settings. The CRN infrastructure supports our overall goals through a rich, interconnected set of shared resources, and collectively, the projects exploit the CRN's geographic diversity and its sophisticated automated data capabilities. CRN projects are designed to pinpoint the ways in which community-based health care systems can best respond to their enrolled members by: 1) ensuring that they receive the right cancer prevention services; 2) devising cancer prevention messages that are readily understood and used; 3) providing treatment that is both effective and cost effective to those patients with cancer; and 4) responding holistically to patients' physical and psychosocial needs. Research in the CRN will be readily applicable across health care settings and will contribute to overall improvements in the quality of cancer care.