TUSM/T-NEMC CENTER FOR NEUROSCIENCE RESEARCH - Genomics Core

计算基因组学核心描述 D3.1。理论基础和使命。计算基因组学核心的目标是提供生物信息学支持 并向塔夫茨大学及其附属机构的神经科学家提供先进的基因组学工具。在.期间 在赠款周期的前1.5年，CORE为神经科学家提供了基本的生物信息学支持。不断增长的 对更复杂的分析工具和高通量基因组技术的需求导致了扩张 在过去的两年里，核心的。与其他塔夫茨中心-GRAPH胃肠病中心合作 和分子心脏病研究所(MCRI)-使CNR能够扩大生物信息学咨询 以及提供精选的基因组学服务，包括实时RT-PCR和基因微阵列 分析。计算基因组学团队目前由博士级别的计算生物学家Lax博士领导 包括执行数据分析和咨询的Christopher Parkin先生和执行数据分析和咨询的岳少女士 监督实时聚合酶链式反应(Q-PCR)服务，并为神经科学家进行微阵列实验。

Computational Genomics Core Description D3.1. Rationale and Mission. The goal of the Computational Genomics Core is to provide bioinformatics support and advanced genomics tools to neuroscientists at Tufts University and its affiliated institutions. During the first 1.5 years of the grant cycle, the core provided basic bioinformatics support to neuroscientists. The growing need for both more sophisticated analytic tools and high throughput genomic technologies led to an expansion of the core over the past 2 years. Partnership with other Tufts Centers - the GRASP gastroenterology center and the Molecular Cardiology Research Institute (MCRI) - enabled the CNR to expand the bioinformatics consultation team as well as provide selected genomics services, including real-time RT-PCR and gene microarray analysis. The computational genomics team is currently led by a PhD-level computational biologist, Dr. Lax Iyer and includes Mr. Christopher Parkin, who performs data analysis and consultation, and Ms. Yue Shao who supervises the real-time PCR (Q-PCR) service and performs microarray experiments for neuroscientists.