Characterization of Fuctional Defective Autoimmune Human CD4+CD25+ Tregs
Characterization of Fuctional Defective Autoimmune Human CD4+CD25+ Tregs
批准号:
8330512
负责人:
David A. Hafler
金额:
$28.91万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2006
资助国家:
美国
项目状态:
已结题
起止时间:
2006-09-15 至 2012-08-31
关键词:
AddressAdoptive Cell TransfersApplications GrantsAutoimmune DiabetesAutoimmune DiseasesAutoimmune ProcessAutoimmunityBiochemicalBloodBlood CirculationCD4 Positive T LymphocytesCell surfaceCellsCoculture TechniquesCollaborationsDataDefectDevelopmentDiabetes MellitusDiseaseDrug Delivery SystemsExhibitsFrequenciesFunctional disorderFutureGenesGenetic TranscriptionGenomeGrantHLA-DR AntigensHistocompatibility Antigens Class IIHumanIL2RA geneImmune systemIn VitroInbred NOD MiceInflammationInstitutesInsulin-Dependent Diabetes MellitusInterleukin-10Interleukin-4InvestigationLibrariesMeasuresMediatingMessenger RNAMicroarray AnalysisMolecular ProfilingMultiple SclerosisMusNeonatalOrganPancreasPathway interactionsPatientsPopulationPreventionPrincipal InvestigatorProductionRNA InterferenceRecombinantsRegulationRegulatory T-LymphocyteRheumatoid ArthritisRodent ModelRoleSiteSorting - Cell MovementSystemT-Cell ActivationT-LymphocyteTestingTherapeuticThymectomyTissuesWorkautoreactive T cellbasecDNA Arrayscytokinediabeticfunctional restorationhuman diseaseloss of functionlymph nodesmRNA Expressionmigrationnon-diabeticnovelperipheral bloodpreventprogramsresearch studytool
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