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Magnetic Particle Imaging Angiography for Chronic Kidney Disease Patients

Magnetic Particle Imaging Angiography for Chronic Kidney Disease Patients
慢性肾病患者的磁粒子成像血管造影
批准号：
8307775
负责人：
STEVEN M CONOLLY
金额：
$41.18万
依托单位：
UNIVERSITY OF CALIFORNIA BERKELEY
依托单位国家：
美国
项目类别：
财政年份：
2011
资助国家：
美国
项目状态：
已结题
起止时间：
2011-08-01 至 2015-05-31
来源：
https://reporter.nih.gov/project-details/8307775
关键词：
AccelerationAmericanAnemiaAngiographyCaliberChronic Kidney FailureComputer softwareContrast MediaCustomFDA approvedFibrosisGadoliniumHumanImageInjection of therapeutic agentIntravenousIodineIonizing radiationKidney DiseasesMagnetic Resonance ImagingMagnetismMeasuresMedicalMethodsMusPatientsPhysiologic pulseRelaxationRenal functionResearchResolutionRoentgen RaysScanningSpeedStagingTestingTimeTissuesVenousX-Ray Computed Tomographyabdominal aortadesignferumoxtrangadolinium oxidehigh riskimaging modalityimprovedin vivoinnovationinstrumentiron oxidemouse modelnanoparticlenovelparticle

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英文摘要
DESCRIPTION (provided by applicant): We will develop hardware, software and novel contrast agents for a new angiographic imaging modality called Magnetic Particle Imaging, which is completely different from X-ray, CT and MRI. Currently available angiographic contrast agents (iodine for X-ray and gadolinium for MRI) are dangerous for Chronic Kidney Disease patients. Magnetic Particle Imaging offers excellent image quality and the contrast agents are completely safe for Chronic Kidney Disease patients. This research will remove the final obstacles to a major medical breakthrough for Chronic Kidney Disease patients.
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