Career Development of Environmental Health Investigators

环境卫生调查员的职业发展

• 批准号: 8250006
• 负责人: John DiGiovanni
• 金额: $ 2.32万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2013-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8250006
• 关键词: Animal Model; Applications Grants; Applied Research; Area; Basic Science; Behavioral; Biological Markers; Clinical; Clinical Research; Clinical Sciences; Collaborations; Core Facility; Development; Discipline; Disease; Ecology; Educational workshop; Environmental Exposure; Environmental Health; Epidemiologic Studies; Epidemiologist; Epidemiology; Faculty; Feedback; Fostering; Funding; Funding Mechanisms; Future; Genetic; Grant; Health Insurance Portability and Accountability Act; Health Sciences; Informatics; Institutional Review Boards; Interdisciplinary Study; Knowledge; Link; Mentors; Mentorship; Methodology; Modeling; Molecular and Cellular Biology; National Institute of Environmental Health Sciences; Obesity; Participant; Population Study; Prevention; Prevention strategy; Protocols documentation; Public Health; Recruitment Activity; Regulation; Research; Research Design; Research Personnel; Research Proposals; Resources; Sample Size; Scientist; Series; Specimen; Techniques; Technology; Training; Translations; Work; Writing; base; career development; experience; improved; interest; meetings; member; multidisciplinary; population based; programs; repository; skills; web site

Specific Aims Future progress in the translation of environmental health research into new strategies for the prevention and control of environmentally related diseases will require the collaboration of clinical, basic and public health (including epidemiological and behavioral) scientists with a broad range of skills. Therefore, a major objective of the Center for Research on Environmental Disease (CRED) is to increase the capacity within the CRED for conducting high-quality multidisciplinary environmental health research that integrates clinical, basic, and applied research strategies and methodologies. This objective will be accomplished through the following specific aims: 1. Cross-train new and existing basic science investigators in the research knowledge and skills required to enhance collaborative environmental science research that integrates basic science methodologies with clinical and/or population-based research. This will be accomplished through the delivery of an annual short course, co-organized by the EHRCDP and members of the Integrative Health Sciences Facilities Core (IHSFC). The short course will be open to trainees and junior faculty, as well as to established Center investigators and will include discussions on study design, study populations (including issues related to access to participants and/or specimens), sample size and other feasibility issues, HIPAA regulations, writing effective IRB protocols as well as integration of biomarkers into epidemiologic and clinical research, and related statistical and informatics issues. The course will also provide participants with a thorough introduction to the IHSFC, including current and future biospecimens in the repositories available to CRED members through this Core. 2. Cross-train new and existing clinical and population-based investigators in the standard techniques and concepts of molecular and cellular biology and genetics to facilitate collaborations and improve the quality of multidisciplinary research. This will be accomplished through the delivery of a short-course, organized by the EHRCDP in collaboration with the four technology based facility cores (FC1-4). The course will provide hands-on experiences with the basic techniques of molecular and cellular biology (including relevant animal models) that are being applied to cutting edge environmental health research. 3. Prepare new investigators (and existing investigators transitioning to environmental health research) to develop independent, NIEHS-funded research programs by increasing their knowledge and grant writing skills through the Environmental Health Grants and Grantsmanship Workshop. This will consist of a 2-day workshop and informal brown bag that will provide a thorough understanding of the types of funding mechanisms available to environmental health investigators at all levels. The workshop will provide hands-on experiences, feedback and mentorship in the planning, writing and review of research proposals, and will equip each participant with resource materials, websites, and contact information that can assist with the successful development of grant applications. 4. Provide models and foster collaborations in the area of translational environmental health research through the Integrative Environmental Health Sciences (IEHS) Seminar Series. This will be a monthly seminar, videoconferenced to each of the CRED campuses, that will link basic science, clinical science and public health science investigators working (either together or separately) on a similar environmental health-related topic. Twice each year, a leading translational environmental scientist from outside the CRED will present in this series and meet with CRED members in an advisory capacity to stimulate and enhance integration of environmental health research within the CRED. 5. Identify, recruit and provide mentoring and professional development for new CRED members, especially junior faculty, and serve as a liaison to facilitate collaborations between these new members and other basic, clinical and population-based investigators. This will be accomplished by establishing formal mentoring teams for junior faculty as well as mid-level faculty new to environmental health research. The EHRCDP will also serve as a "broker" to facilitate linkages between new and existing CRED members from different disciplines but with similar research interests (i.e., a basic scientist working on obesity and wanting to link with a clinical trialist; an epidemiologist wanting to collaborate with a basic scientist to develop and use biomarkers of environmental exposure).

具体目标 将环境卫生研究转化为新的预防和 控制与环境有关的疾病将需要临床、基础和公共卫生的合作 （包括流行病学和行为）科学家与广泛的技能。因此，一个主要目标 环境疾病研究中心（CRED）的目标是提高CRED的能力， 开展高质量的多学科环境卫生研究，整合临床，基础和 应用研究战略和方法。这一目标将通过以下方式实现： 具体目标： 1.交叉培训新的和现有的基础科学研究人员所需的研究知识和技能 加强整合基础科学方法的环境科学合作研究 临床和/或基于人口的研究。这将通过提供一个 年度短期课程，由EHRCDP和综合健康科学的成员共同组织 设施核心（IHSFC）。短期课程将开放给学员和初级教师，以及 已建立的中心研究者，并将包括关于研究设计、研究人群 （包括与接触参与者和/或标本有关的问题）、样本量和其他可行性 问题，HIPAA法规，编写有效的IRB方案以及将生物标志物整合到 流行病学和临床研究，以及相关的统计和信息学问题。该课程还将 为参与者提供IHSFC的全面介绍，包括当前和未来 生物标本的储存库提供给CRED成员通过这个核心。 2.交叉培训新的和现有的临床和基于人群的研究者的标准技术， 分子和细胞生物学和遗传学的概念，以促进合作，提高 多学科研究的质量。这将通过提供短期课程来实现， 由EHRCDP与四个基于技术的设施核心（FC 1 - 4）合作组织。的 课程将提供分子和细胞生物学基本技术的实践经验 （包括相关的动物模型）正在应用于尖端的环境健康 research. 3.准备新的研究者（以及过渡到环境健康研究的现有研究者）， 通过增加他们的知识和资助，发展独立的，NIEHS资助的研究项目 通过环境卫生赠款和赠款讲习班的写作技巧。这将包括 为期2天的研讨会和非正式的棕色袋子，将提供一个彻底的了解类型的 向各级环境卫生调查人员提供的供资机制。讲习班将 在研究的规划、撰写和审查方面提供实践经验、反馈和指导 建议，并将为每个参与者提供资源材料，网站和联系信息 这可以帮助成功开发赠款申请。 4.在转化环境健康研究领域提供模型并促进合作 综合环境健康科学（IEHS）系列研讨会。这将是一个每月 研讨会，视频会议到每个CRED校园，这将链接基础科学，临床科学 和公共卫生科学调查人员（无论是一起或单独）在一个类似的 与环境健康有关的话题。每年两次，一位著名的环境科学家 来自外部的CRED将在本系列中介绍，并与CRED成员进行咨询 促进和加强环境卫生研究在CRED内的整合的能力。 5.为新的CRED成员识别、招募并提供指导和专业发展， 特别是初级教师，并作为联络，以促进这些新成员之间的合作 以及其他基础、临床和基于人群的研究者。这将通过建立 为初级教师和中级教师提供正式的环境卫生指导团队 research. EHRCDP还将充当“经纪人”，促进新的和现有的联系 来自不同学科但具有相似研究兴趣的CRED成员（即，一名基础科学家 致力于肥胖研究，并希望与临床试验者建立联系;一位流行病学家希望与 与基础科学家一起开发和使用环境暴露的生物标志物）。