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中文摘要
翻译
项目总结(见说明): 方案项目的全面管理将通过行政核心执行,以 确保达到研究计划的目标。这一核心的功能包括沟通、协调、 记录保存、财务管理、组织和对项目的监督。具体来说, 该核心提供了处理人员、订购设备和用品、 编写报告和其他书面通信,维护和核对账目。 行政核心安排执行委员会的定期会议,每月进展一次 与项目负责人会面,以及每两个月举行一次座谈会。此外,它的协调功能还包括 核心人员将安排外部咨询委员会访问时的旅行计划和住宿 中心和更频繁地通过电子邮件传播信息,以征求他们的意见和建议 持续存在的问题,特别是在准备这份修订的申请书期间。该核心还提供了 交流信息和想法的论坛,以及协调两国联合出版物的数据 项目。组织结构,由一个执行委员会和一个外部咨询组成 委员会的目的是在综合努力中最大限度地发挥协同作用,以实现 计划项目的目标。将继续维护方案项目赠款的网站,以 确保快速、高效地交换数据和想法。最后,管理核心将提供 全面协调预算的财政管理和向委员会报告的必要职能 国家卫生研究院。通过核心支助履行这些行政职能将得到加强 这项研究计划的协作和整合。计划项目的责任,包括 科学和生产力的质量,将通过与项目负责人和 每年与外部咨询委员会成员举行会议。
英文摘要
PROJECT SUMMARY (See instructions): The overall administration of the Program Project will be performed through the Administrative Core to ensure that the goals of the research program are met. Functions of this core include communication, coordination, record keeping, financial management, organization and oversight to the program. Specifically, the core provides a framework for the processing of personnel, the ordering of equipment and supplies, the preparation of reports and other written communications, and the maintenance and reconciliation of accounts. The administrative core arranges the regular meetings of the executive committee, a monthly progress meeting with project leaders, as well as a bi-monthly colloquium. In addition, the co-ordination function of the core will arrange travel plans and accommodation ofthe Extemal Advisory Committee when they visit the Center and the more frequent circulation of information by emails to solicit their counsel and advice with ongoing problems, particularly during the preparation of this revised application. The core also provides a forum for the exchange of infonnation and ideas as well as to coordinate data for joint publications between projects. The organizational structure, consisting of an executive committee and an extemal advisory committee, is designed to maximize the level of synergy in an integrated effort to accomplish the overall goals of the program project. A web-site for the program project grant will continue to be maintained to ensure rapid and efficient exchange of data and ideas. Finally, the administrative core will provide the necessary function of overall coordination of fiscal management of the budgets and of the reporting to the NIH. Performance of these administrative functions through the support of the core will enhance collaboration and integration of this research program. Accountability ofthe program project, including the quality of science and productivity, will be achieved by monthly program evaluation with project leaders and annually with members ofthe extemal advisory committee.
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MECHANISM OF BYSTANDER MUTAGENESIS
MECHANISM OF BYSTANDER MUTAGENESIS
ADMINISTRATIVE CORE
Project 1: Genotoxic & Cell Signaling Pathways of As in Mammalian Cells
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