Extension of the World Trade Center Registry

描述（由申请人提供）：世界贸易中心健康登记处（WTCHR）是美国历史上最大的灾后暴露健康登记处，正在跟踪71437名直接受影响的人，他们参加了911相关的救援/恢复工作，或在911当天在曼哈顿下城生活、工作或上学。目标是确定9/11世贸中心灾难对身心健康的长期影响；向参与者和其他暴露者、公众和科学界传播调查结果和建议；分享与9/11相关的资源和服务信息；并为医疗保健政策和灾难应对计划提供信息。具体目标是：1)通过继续WTCHR研究项目，扩大关于9/11对健康的长期影响的知识；2)开展社区活动，以应对登登者和其他暴露于9/11事件的人的身心健康问题和特定医疗保健需求；3)保持该登记处作为未来研究的宝贵公共卫生资源。

DESCRIPTION (provided by applicant): The World Trade Center Health Registry (WTCHR), the largest post-disaster exposure health registry in U.S. history, is following a diverse cohort of 71,437 directly affected people who performed 9/11-related rescue/recovery work or lived, worked or attended school in lower Manhattan on 9/11/01. The goals are to identify the long-term physical and mental health effects of the 9/11 WTC disaster; disseminate findings and recommendations to enrollees and others exposed, the public, and the scientific community; share information about 9/11-related resources and services; and inform healthcare policy and disaster response planning. Specific aims are to: 1) Expand knowledge about the long-term health effects of 9/11 by continuing the WTCHR research program; 2) Conduct community activities to respond to the physical and mental health concerns and specific healthcare needs of enrollees and others exposed to 9/11; and 3) Maintain the Registry as a valuable public health resource for future research. Aim 1 entails conducting priority epidemiological analyses using data from the baseline (2003-04) and follow-up (2006-08) surveys, including analyses to assess risk factors for the development or persistence of serious respiratory and mental health conditions over time; developing and conducting a second follow-up survey of all enrollees using multiple survey modes (paper, web and telephone) to ascertain the health status and 9/11-related healthcare needs of the cohort ~10 years after 9/11; matching with vital records, cancer registries, and the national death certificate system for cancer and mortality assessments; and investigating other potential emerging health conditions through public health surveillance, medical record review and follow-up case-control studies. The WTCHR will also facilitate independent and collaborative 9/11-related research by providing qualified external researchers with de-identified data and access to enrollee subgroups for re