Extension of the World Trade Center Registry

描述(由申请人提供)：世界贸易中心健康注册中心(WTCHR)是美国历史上最大的灾后暴露健康注册中心，正在跟踪2001年9月11日在曼哈顿下城进行与9/11相关的救援/恢复工作或生活、工作或上学的71,437名直接受影响的人的多样化队列。目标是确定9/11世贸中心灾难对身心健康的长期影响；向参与者和其他受影响的人、公众和科学界传播调查结果和建议；共享与9/11相关的资源和服务的信息；并为医疗保健政策和灾难应对规划提供信息。具体目标是：1)通过继续开展9/11事件研究计划，扩大有关9/11事件长期健康影响的知识；2)开展社区活动，回应9/11事件参与者和其他受9/11事件影响的人的身心健康关切和具体的医疗保健需求；3)保持登记处作为未来研究的宝贵公共卫生资源。 目标1要求利用基线调查(2003-04年)和后续调查(2006-08年)的数据进行优先流行病学分析，包括分析以评估严重呼吸系统和精神健康状况随时间发展或持续的风险因素；利用多种调查模式(纸质、网络和电话)对所有参与者进行第二次后续调查，以确定9/11事件后10年的健康状况和与9/11有关的保健需求；与生命记录、癌症登记和国家癌症死亡证书系统进行匹配，并进行死亡率评估；并通过公共卫生监测、医疗记录审查和后续病例对照研究调查其他潜在的新出现的健康状况。WTCHR还将通过向合格的外部研究人员提供未确认身份的数据和访问Re的参与者分组，促进独立和协作的9/11相关研究。

DESCRIPTION (provided by applicant): The World Trade Center Health Registry (WTCHR), the largest post-disaster exposure health registry in U.S. history, is following a diverse cohort of 71,437 directly affected people who performed 9/11-related rescue/recovery work or lived, worked or attended school in lower Manhattan on 9/11/01. The goals are to identify the long-term physical and mental health effects of the 9/11 WTC disaster; disseminate findings and recommendations to enrollees and others exposed, the public, and the scientific community; share information about 9/11-related resources and services; and inform healthcare policy and disaster response planning. Specific aims are to: 1) Expand knowledge about the long-term health effects of 9/11 by continuing the WTCHR research program; 2) Conduct community activities to respond to the physical and mental health concerns and specific healthcare needs of enrollees and others exposed to 9/11; and 3) Maintain the Registry as a valuable public health resource for future research. Aim 1 entails conducting priority epidemiological analyses using data from the baseline (2003-04) and follow-up (2006-08) surveys, including analyses to assess risk factors for the development or persistence of serious respiratory and mental health conditions over time; developing and conducting a second follow-up survey of all enrollees using multiple survey modes (paper, web and telephone) to ascertain the health status and 9/11-related healthcare needs of the cohort ~10 years after 9/11; matching with vital records, cancer registries, and the national death certificate system for cancer and mortality assessments; and investigating other potential emerging health conditions through public health surveillance, medical record review and follow-up case-control studies. The WTCHR will also facilitate independent and collaborative 9/11-related research by providing qualified external researchers with de-identified data and access to enrollee subgroups for re