Environmental Contaminants And Risk Of Endometriosis

环境污染物和子宫内膜异位症的风险

• 批准号: 8351164
• 负责人: Germaine Louis
• 金额: $ 0.4万
• 依托单位: EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8351164
• 关键词: Behavior; Chemical Exposure; Chemicals; Development; Diagnosis; Environmental Pollution; Environmental Risk Factor; Laparoscopy; Laparotomy; Life Style; Operative Surgical Procedures; Pathway interactions; Polychlorinated Biphenyls; Woman; Work; cohort; design; endometriosis; environmental chemical; in utero; organochlorine pesticide

We are continuing to explore the effect of polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) in relation to the diagnosis of endometriosis, particularly in the context of lifestyle behaviors. Much of our effort to date has focused on PCBs. Our current analyses are focusing on OCPs and the development of endometriosis. Again, our focus is chemical exposure in the context of lifestyle, given that many lifestyle behaviors utilize similiar enzymatic pathways for clearance. This work was designed to guide the development of the analytic plan for the ENDO Study.

我们正在继续探索多氯联苯（PCBs）和有机氯农药（OCPs）在子宫内膜异位症诊断中的作用，特别是在生活方式行为的背景下。迄今为止，我们的大部分工作都集中在多氯联苯上。我们目前的分析集中在ocp和子宫内膜异位症的发展。再一次，我们的重点是生活方式背景下的化学暴露，因为许多生活方式行为利用类似的酶清除途径。这项工作旨在指导ENDO研究分析计划的制定。