SEER RRSS Improving SES Data: Linkage State Vital Records, Birth Certificate Data

SEER RRSS 改进 SES 数据：链接状态人口记录、出生证明数据

• 批准号: 8351002
• 负责人: Antoinette Marie Stroup
• 金额: $ 8.78万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-30 至 2012-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8351002
• 关键词: Adult; Affect; Area; Birth Certificates; California; Censuses; Cessation of life; Childhood; Code; Collaborations; Data; Data Linkages; Diagnosis; Education; Family; Female Breast Carcinoma; Goals; Household; Incidence; Income; Individual; Industry; Life; Literature; Malignant Childhood Neoplasm; Malignant Neoplasms; Measurement; Measures; Methodology; Occupations; Population; Population Database; Records; Registries; Risk; Sampling; Site; Surveys; Time; Utah; base; cancer health disparity; cancer risk; cancer site; improved; interest

Numerous studies have observed that lower SES is associated with increased risk of incident cancer for some sites and reduced survival for many cancer sites. One exception is for female breast cancer as higher SES is associated with increased risk and better survival. However, evidence of the impact of SES is limited in the fact that SES is often measured at an aggregate or area level (e.g., mean household income for a zip code or census tract, proportion poor in a block group). This proposal will implement a strategy that permits a direct measurement of SES at the individual level through record linkage to state birth certificate records available in the Utah Population Database. In possible collaboration with other SEER registries, this proposal will assess the feasibility of applying Utah¿s linkage methodologies to a California population of pediatric cancer cases born on or after 1997, and compare and contrast results with the comparable pediatric population in Utah. This strategy may provide a better understanding of health and cancer disparities in terms of SES. The understanding of how SES affects these risks remains surprisingly underdeveloped. This deficiency in the literature is partly attributable to the fact that SES is often measured at an aggregate or area level (e.g., mean household income for a zip code or census tract, proportion poor in a block group). While there is no question that spatial indicators of SES are important, they are not substitutes for individual or family level measures of SES. Moreover, spatial indicators are treated as a static measure so that upward or downward changes in SES are not considered. Finally, the spatial data are often based on SES at the time of diagnosis, death, or at the time of a survey when it is likely that the SES value of interest could be from earlier in life. A review of 124 studies examining SES effects on cancer risk shows that while only about 25 percent collected individual SES data, most of these were based on small samples (N<5000) and where SES was measured once at the time of the survey.

大量研究发现，较低的 SES 与某些部位发生癌症的风险增加以及许多癌症部位的生存率降低有关。女性乳腺癌是一个例外，因为较高的 SES 与增加的风险和更好的生存率相关。然而，社会经济地位影响的证据有限，因为社会经济地位通常是在总体或地区层面上衡量的（例如，邮政编码或人口普查区的平均家庭收入、街区组中的贫困人口比例）。该提案将实施一项战略，允许通过与犹他州人口数据库中可用的州出生证明记录的记录链接，在个人层面直接衡量社会经济地位。在可能与其他 SEER 登记处合作的情况下，该提案将评估将犹他州的关联方法应用于 1997 年或之后出生的加州儿童癌症病例人群的可行性，并将结果与​​犹他州的可比儿科人群进行比较和对比。这一策略可以让人们更好地了解社会经济地位方面的健康和癌症差异。令人惊讶的是，人们对社会经济地位如何影响这些风险的理解仍然不够深入。文献中的这种缺陷部分归因于这样一个事实：社会经济地位通常是在总体或地区层面上衡量的（例如，邮政编码或人口普查区的平均家庭收入、街区组中的贫困人口比例）。毫无疑问，社会经济地位的空间指标很重要，但它们不能替代个人或家庭层面的社会经济地位衡量标准。此外，空间指标被视为静态指标，因此不考虑社会经济地位的向上或向下变化。最后，空间数据通常基于诊断时、死亡时或调查时的 SES，此时感兴趣的 SES 值可能来自生命早期。对 124 项研究 SES 对癌症风险影响的回顾表明，虽然只有约 25% 的研究收集了个人 SES 数据，但其中大多数都是基于小样本 (N<5000)，并且在调查时测量了一次 SES。